Announcements Trials

Conditions

Thoracic 4Other 1

Drug Classes

Anti-PD-1 17Anti-PD-L1 10EGFR inhibitor 10ALK inhibitor 7Platinum agent 5Anti-CTLA-4 4Anti-EGFR-HGFR bispecific 4Antifolate 4MET inhibitor 4RET inhibitor 4BRAF inhibitor 3ERBB2 inhibitor 3MEK inhibitor 3ROS1 inhibitor 3Alkylating agent 2Anti-DLL3-CD3 bispecific 2Anti-HER2 ADC 2KRAS inhibitor 2TRK inhibitor 2Topoisomerase II inhibitor 2Anti-HER2-HER3 bispecific 1Anti-TROP2 ADC 1Anti-VEGFR 1Anti-c-Met ADC 1Taxane 1
Anti-EGFR-HGFR bispecific × Thoracic × Clear all

4 Announcements

2024-09-19

FDA approves amivantamab-vmjw with carboplatin and pemetrexed for non-small cell lung cancer with EGFR exon 19 deletions or L858R mutations

Trial
MARIPOSA-2
Drugs
Rybrevant (amivantamab-vmjw) · Anti-EGFR-HGFR bispecific antibody, carboplatin · Platinum agent, pemetrexed · Antifolate
Condition
Thoracic
2024-08-19

FDA approves lazertinib with amivantamab-vmjw for non-small lung cancer

Trial
MARIPOSA
Drugs
Lazcluze (lazertinib) · EGFR inhibitor, Rybrevant (amivantamab-vmjw) · Anti-EGFR-HGFR bispecific antibody
Condition
Thoracic
2024-03-01

FDA approves amivantamab-vmjw for EGFR exon 20 insertion-mutated non-small cell lung cancer indications

Trial
PAPILLON
Drugs
Rybrevant (amivantamab-vmjw) · Anti-EGFR-HGFR bispecific antibody, carboplatin · Platinum agent, pemetrexed · Antifolate
Condition
Thoracic
2021-05-21

FDA grants accelerated approval to amivantamab-vmjw for metastatic non-small cell lung cancer

Trial
CHRYSALIS
Drug
Rybrevant (amivantamab-vmjw) · Anti-EGFR-HGFR bispecific antibody
Condition
Thoracic
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