Announcements Trials
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Phase

Phase 2 29477Phase NA 26226Phase 1 16449Phase 3 9458Phase 1/2 8397Phase 4 2568Phase EARLY_PHASE1 1920Phase 2/3 1465

Status

Completed 52567Unknown 19742Recruiting 18789Terminated 11020Active not recruiting 7671Not yet recruiting 6189Withdrawn 4072Enrolling by invitation 740Suspended 496No longer available 218Available 101Approved for marketing 97Temporarily not available 10

Sponsor Class

OTHER 83738INDUSTRY 27129NIH 5190NETWORK 2575OTHER_GOV 2469FED 279UNKNOWN 278INDIV 54

Study Type

Interventional 95958Observational 25328Expanded_access 426

Sponsor

Cancer Type

Gastrointestinal 23775Breast 15569Thoracic 12843Genitourinary 11951Lymphoid 10948Other hematologic neoplasm 9747Gynecologic 7575Head & Neck 6461CNS 6238Dermatologic 4976Tumor-Agnostic 4746Plasma cell 3997Other solid neoplasm 3901Sarcoma 3753Myeloid 2755Endocrine 1800Classical hematology 1128Other 894NET 619Other neoplasm 359

Conditions

Breast Neoplasms 13234Neoplasms 10563Carcinoma, Non-Small-Cell Lung 6926Prostatic Neoplasms 6316Colorectal Neoplasms 5982Lung Neoplasms 5133Multiple Myeloma 3603Pancreatic Neoplasms 3593Neoplasm Metastasis 3536Leukemia, Myeloid, Acute 3527Carcinoma, Hepatocellular 3303Ovarian Neoplasms 3201Melanoma 3157Stomach Neoplasms 3083Lymphoma 2989Head and Neck Neoplasms 2634Recurrence 2571Precursor Cell Lymphoblastic Leukemia-Lymphoma 2502Leukemia 2366Colonic Neoplasms 2340Brain Neoplasms 2335Lymphoma, Non-Hodgkin 2271Uterine Cervical Neoplasms 2208Rectal Neoplasms 2201Glioblastoma 2030Leukemia, Lymphocytic, Chronic, B-Cell 2000Carcinoma, Renal Cell 1923Squamous Cell Carcinoma of Head and Neck 1899Lymphoma, Follicular 1857Esophageal Neoplasms 1809

Interventions

Cisplatin 3222Cyclophosphamide 3212Carboplatin 2999Radiotherapy 2798Paclitaxel 2732Gemcitabine 2587pembrolizumab 2403Bevacizumab 2219Docetaxel 2205Fluorouracil 1854Capecitabine 1848Oxaliplatin 1755Dexamethasone 1611Nivolumab 1589Doxorubicin 1509Rituximab 1496Magnetic Resonance Spectroscopy 1405Etoposide 1347Irinotecan 1251Leucovorin 1230Drug Therapy 1216Cytarabine 1133Pemetrexed 1085fludarabine 1070Specimen Handling 1037Vincristine 971Cetuximab 950Trastuzumab 950Prednisone 949Lenalidomide 943

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

121,971 trials
RecentStart dateEnrollment
NCT00001238 2026-07-17

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

National Institutes of Health Clinical Center (CC)

Recruiting
5,000 enrolled
EndocrineGenitourinary

Hereditary leiomyomatosis and renal cell cancer, Carcinoma, Renal Cell, Kidney Neoplasms, Pheochromocytoma

NCT00001276 2026-07-17

Diagnosing and Treating Low Blood Sugar Levels

National Institutes of Health Clinical Center (CC)

Recruiting
1,500 enrolled
Endocrine

Hypoglycemia, Insulinoma

NCT00001403 2026-07-17

Study of Proteus Syndrome and Related Congenital Disorders

National Institutes of Health Clinical Center (CC)

Recruiting
1,500 enrolled

Abnormalities, Multiple, Growth Disorders, Proteus Syndrome

NCT00001452 2026-07-17

Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex

National Institutes of Health Clinical Center (CC)

Completed
1,387 enrolled
Endocrine

Cushing Syndrome, Peutz-Jeghers Syndrome, Pituitary Neoplasms, Carney Complex

NCT00001532 2026-07-17

Role of Genetic Factors in the Development of Lung Disease

National Institutes of Health Clinical Center (CC)

Recruiting
3,500 enrolled

Asthma, Cystic Fibrosis, Lung Diseases, Pulmonary Fibrosis, Tuberous Sclerosis, Sarcoidosis, Pulmonary, alpha 1-Antitrypsin Deficiency

NCT00001813 2026-07-17

Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

National Institutes of Health Clinical Center (CC)

Completed
709 enrolled
Dermatologic

Cockayne Syndrome, Skin Diseases, Genetic, Skin Neoplasms, Xeroderma Pigmentosum, Trichothiodystrophy Syndromes

NCT00004847 2026-07-17

Diagnosis of Pheochromocytoma

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
3,000 enrolled
Endocrine

Endocrine System Diseases, Pheochromocytoma

NCT00005902 2026-07-17

Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease

National Institutes of Health Clinical Center (CC)

Active not recruiting
250 enrolled

Cysts, von Hippel-Lindau Disease, Hemangioblastoma

NCT00024804 2026-07-17

A Natural History Study of Bone and Mineral Disorders

National Institutes of Health Clinical Center (CC)

Recruiting
1,000 enrolled

Bone Diseases, Osteomalacia, Osteoporosis

NCT00027326 2026-07-17

Collection of Blood and Urine From Patients Undergoing Radiation Therapy

National Institutes of Health Clinical Center (CC)

Enrolling by invitation
1,000 enrolled
Tumor-Agnostic

Carcinoma, Neoplasms

NCT00032513 2026-07-17

Genetic Studies of Chronic Active Epstein-Barr Disease

National Institutes of Health Clinical Center (CC)

Recruiting
300 enrolled
Lymphoid

Herpes Simplex, Infectious Mononucleosis, Lymphoproliferative Disorders, Virus Diseases, Epstein-Barr Virus Infections

NCT00040222 2026-07-17

Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

National Institutes of Health Clinical Center (CC)

Completed
377 enrolled
BreastGynecologic

Breast Cancer, Familial, Breast Neoplasms, Hamartoma Syndrome, Multiple, Ovarian Neoplasms, Peutz-Jeghers Syndrome, Li-Fraumeni Syndrome, Risk Reduction Behavior

NCT00050752 2026-07-17

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

National Institutes of Health Clinical Center (CC)

Recruiting
1,130 enrolled
Genitourinary

Kidney Neoplasms, Leiomyoma

NCT00086567 2026-07-17

Predictors of Relapse of Ovarian, Peritoneal, and Fallopian Tube Cancers

National Institutes of Health Clinical Center (CC)

Completed
119 enrolled
Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Peritoneal Neoplasms

NCT00092222 2026-07-17

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

National Institutes of Health Clinical Center (CC)

Phase 2 Active not recruiting
75 enrolled
Lymphoid

Multi-centric Castleman's Disease, Macular dystrophy, corneal type 1, Lymphadenopathy, Lymphoproliferative Disorders, Neoplasms, HIV Infections

NCT00106925 2026-07-17

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

National Institutes of Health Clinical Center (CC)

Recruiting
1,000 enrolled
Plasma cell

Graft vs Host Disease, Neoplasms, Plasma Cell

NCT00340405 2026-07-17

Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China

National Institutes of Health Clinical Center (CC)

Completed
9,759 enrolled
Thoracic

Lung Neoplasms

NCT00341276 2026-07-17

Esophageal Cancer Genetics Studies

National Institutes of Health Clinical Center (CC)

Completed
7,705 enrolled
Gastrointestinal

Esophageal Neoplasms, Neoplasms

NCT00342654 2026-07-17

Nutrition Intervention Trials in Linxian Follow-up Study

National Institutes of Health Clinical Center (CC)

Completed
32,902 enrolled
Gastrointestinal

Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT00342888 2026-07-17

Case-Control Study of Pesticides and Childhood Leukemia

National Institutes of Health Clinical Center (CC)

Completed
629 enrolled
Other hematologic neoplasm

Leukemia, Neoplasms

NCT00508443 2026-07-17

Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)

M.D. Anderson Cancer Center

Phase 1/2 Active not recruiting
150 enrolled
BreastDermatologicGastrointestinalLymphoidSarcomaThoracic

Urogenital Diseases, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Neoplasms, Sarcoma, Spinal Diseases, Spinal Neoplasms

NCT00598351 2026-07-17

Natural History Study of Patients With Neurofibromatosis Type 2

National Institutes of Health Clinical Center (CC)

Recruiting
269 enrolled
CNS

Ependymoma, Meningioma, Neurilemmoma, Neuroma, Acoustic, Spinal Cord Neoplasms, Neurofibromatoses

NCT00707473 2026-07-17

Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer

M.D. Anderson Cancer Center

Phase 2 Terminated
31 enrolled 11 charts

Sinonasal undifferentiated carcinoma, Paranasal Sinus Neoplasms

NCT00867269 2026-07-17

Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

National Institutes of Health Clinical Center (CC)

Recruiting
950 enrolled
Classical hematology

Autoimmune Diseases, Immunologic Deficiency Syndromes, Opportunistic Infections, Warts, Meningitis, Cryptococcal, T-Lymphocytopenia, Idiopathic CD4-Positive

NCT00992303 2026-07-17

Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants

University of Texas Southwestern Medical Center

Recruiting
10,000 enrolled
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT01087294 2026-07-17

Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
85 enrolled
LymphoidOther hematologic neoplasm

Hodgkin Disease, Lymphoma, Non-Hodgkin, Leukemia, B-Cell, Lymphoma, B-Cell

NCT01087333 2026-07-17

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

National Institutes of Health Clinical Center (CC)

Recruiting
1,263 enrolled
DermatologicLymphoidOther hematologic neoplasm

Hemolytic-Uremic Syndrome, Leukemia, Hairy Cell, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, T-Cell, Cutaneous, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01109394 2026-07-17

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

National Institutes of Health Clinical Center (CC)

Recruiting
6,035 enrolled
CNSGenitourinaryOther solid neoplasmSarcoma

Kidney Neoplasms, Neoplasms, Neuroblastoma, Retinoblastoma, Sarcoma

NCT01352962 2026-07-17

Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
18 enrolled
GastrointestinalGenitourinaryGynecologicThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Ureteral Neoplasms, Urethral Neoplasms

NCT01362803 2026-07-17

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
99 enrolled 1 FDA
CNS

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT01370980 2026-07-17

Collaborative Seamless Care in Oncology : Measure and Reinforce Safety and Adherence to Oral Cancer Treatment

Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland

Completed
43 enrolled

Neoplasms, Patient Acceptance of Health Care, Patient Compliance, Medication Adherence

NCT01660984 2026-07-17

Natural History Study of Children and Adults With Medullary Thyroid Cancer

National Institutes of Health Clinical Center (CC)

Recruiting
259 enrolled
EndocrineHead & Neck

Pheochromocytoma, Thyroid Neoplasms, Carcinoma, Medullary

NCT01834001 2026-07-17

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

National Institutes of Health Clinical Center (CC)

Recruiting
300 enrolled
Genitourinary

Prostatic Neoplasms

NCT01949662 2026-07-17

Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
93 enrolled 14 charts
Other hematologic neoplasm

Delirium, Hematologic Neoplasms, Neurotoxicity Syndromes

NCT02071901 2026-07-17

Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

Case Comprehensive Cancer Center

Phase 2 Completed
31 enrolled 15 charts
Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT02091999 2026-07-17

A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumors That Express Nectin-4

Astellas Pharma Inc

Phase 1 Completed
213 enrolled
GenitourinaryOther solid neoplasm

Metastatic Urothelial Cancer and Other Malignant Solid Tumors

NCT02146170 2026-07-17

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

National Institutes of Health Clinical Center (CC)

Recruiting
2,000 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT02153957 2026-07-17

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
36 enrolled
CNS

Brain Neoplasms, Motor Activity

NCT02154022 2026-07-17

Collection of Pharmacokinetic Samples From People With Unanticipated Response, Significant Toxicity or Concern of Future Toxicity

National Institutes of Health Clinical Center (CC)

Enrolling by invitation
100 enrolled
Tumor-Agnostic

Neoplasms

NCT02416388 2026-07-17

BIG-1

University Hospital, Angers

Phase 2/3 Recruiting
3,100 enrolled
Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02423057 2026-07-17

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
27 enrolled
Tumor-Agnostic

Neoplasms

NCT02473757 2026-07-17

Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell Studies

National Institutes of Health Clinical Center (CC)

Enrolling by invitation
1,000 enrolled
LymphoidOther hematologic neoplasmPlasma cell

Multiple Myeloma, Leukemia, B-Cell, Hematologic Neoplasms

NCT02484404 2026-07-17

Phase I/II Study of the Anti-Programmed Death Ligand-1 Durvalumab Antibody (MEDI4736) in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Can...

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
268 enrolled
BreastGastrointestinal

Breast Neoplasms, Colorectal Neoplasms

NCT02544022 2026-07-17

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

National Institutes of Health Clinical Center (CC)

Recruiting
476 enrolled
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02603887 2026-07-17

Pembrolizumab in Treating Patients With Intermediate or High-Risk Smoldering Multiple Myeloma

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Active not recruiting
20 enrolled 12 charts
Plasma cell

Smoldering Multiple Myeloma

NCT02721732 2026-07-17

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
157 enrolled 26 charts
CNSEndocrineGenitourinary

Adrenal Cortex Neoplasms, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms, Unknown Primary, Paraganglioma, Penile Neoplasms, Pheochromocytoma, Carcinoma, Small Cell, Vascular Neoplasms

NCT02902757 2026-07-17

FDG PET/CT in Monitoring Very Early Therapy Response in Patients With Glioblastoma

Jonsson Comprehensive Cancer Center

Phase NA Completed
7 enrolled
CNS

Glioblastoma

NCT02967276 2026-07-17

METDEXA-MM

University of Campinas, Brazil

Phase 2 Terminated
28 enrolled
Plasma cell

Multiple Myeloma

NCT03069378 2026-07-17

A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

Memorial Sloan Kettering Cancer Center

Phase 2 Active not recruiting
41 enrolled 8 charts
Sarcoma

Neoplasm Metastasis, Sarcoma

NCT03115333 2026-07-17

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Eastern Cooperative Oncology Group

Phase NA Active not recruiting
146 enrolled
CNSSarcoma

Glioblastoma, Gliosarcoma

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