2023-08-02FDA approves trifluridine and tipiracil with bevacizumab for previously treated metastatic colorectal cancerTrial SUNLIGHTDrugs LONSURF (trifluridine and tipiracil) · Fluoropyrimidine, bevacizumab · Anti-VEGFR antibodyConditionGastrointestinal
2020-05-29FDA approves ramucirumab plus erlotinib for first-line metastatic NSCLCTrial RELAYDrugs CYRAMZA (ramucirumab) · Anti-VEGFR antibody, erlotinib · EGFR inhibitorConditionThoracic
2020-05-29FDA approves atezolizumab plus bevacizumab for unresectable hepatocellular carcinomaTrial IMbrave150Drugs TECENTRIQ (atezolizumab) · Anti-PD-L1 antibody, AVASTIN (bevacizumab) · Anti-VEGFR antibodyConditionGastrointestinal
2020-05-08FDA approves olaparib plus bevacizumab as maintenance treatment for ovarian, fallopian tube, or primary peritoneal cancersTrial DUO-ODrugs LYNPARZA (olaparib) · PARP inhibitor, bevacizumab · Anti-VEGFR antibodyConditionGynecologic
2019-05-10FDA approves ramucirumab for hepatocellular carcinomaTrial REACH-2Drug CYRAMZA (ramucirumab) · Anti-VEGFR antibodyConditionGastrointestinal
2018-06-13FDA approves bevacizumab in combination with chemotherapy for ovarian cancerDrugs Avastin (bevacizumab) · Anti-VEGFR antibody, carboplatin · Platinum agent, paclitaxel · TaxaneConditionGynecologic
2017-09-14FDA approves first biosimilar for cancer treatmentDrugs Mvasi (bevacizumab-awwb) · Anti-VEGFR antibody, Avastin (bevacizumab) · Anti-VEGFR antibody
2014-12-12Ramucirumab (Cyramza)Drugs Cyramza (ramucirumab) · Anti-VEGFR antibody, docetaxel · Taxane, paclitaxel · Taxane
2014-11-14Bevacizumab solution in combination with PaclitaxelDrugs Avastin (bevacizumab solution for intravenous infusion) · Anti-VEGFR antibody, Avastin (intravenous infusion) , paclitaxel · Taxane
2014-11-05Ramucirumab in combination with paclitaxelDrugs Cyramza (ramucirumab) · Anti-VEGFR antibody, paclitaxel · Taxane
2014-08-14Bevacizumab solutionDrugs Avastin (bevacizumab solution for intravenous infusion) · Anti-VEGFR antibody, Avastin (intravenous infusion)
2009-07-31Bevacizumab (Avastin) in Combination with Interferon AlfaDrugs Avastin (bevacizumab) · Anti-VEGFR antibody, interferon alfa
2008-02-22Bevacizumab Granted Accelerated ApprovalDrugs Avastin (bevacizumab) · Anti-VEGFR antibody, paclitaxel · Taxane