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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 2Head & Neck 2Gynecologic 2Gastrointestinal 2Breast 2Sarcoma 1Other solid neoplasm 1Genitourinary 1Dermatologic 1CNS 1

Conditions

Triple Negative Breast Neoplasms 16Carcinoma, Non-Small-Cell Lung 7Pancreatic Neoplasms 6Melanoma 6Breast Neoplasms 6Carcinoma, Renal Cell 5Lung Neoplasms 4Squamous Cell Carcinoma of Head and Neck 3Head and Neck Neoplasms 3Colorectal Neoplasms 3Uterine Cervical Neoplasms 2Stomach Neoplasms 2Small Cell Lung Carcinoma 2Sarcoma 2Ovarian Neoplasms 2Neoplasms 2Liver Neoplasms 2Esophageal Squamous Cell Carcinoma 2Endometrial Neoplasms 2Colonic Neoplasms 2Carcinoma, Transitional Cell 2Carcinoma, Ovarian Epithelial 2Carcinoma, Hepatocellular 2Anus Neoplasms 2Adenocarcinoma of Lung 2Adenocarcinoma Of Esophagus 2Adenocarcinoma 2Uveal Melanoma 1Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1

Interventions

pembrolizumab 4spartalizumab 2Trastuzumab 2Psychiatric Rehabilitation 2Paclitaxel 2Irinotecan 2Carboplatin 2tislelizumab 1tipifarnib 1nanocis 1entinostat 1Vorinostat 1Thalidomide 1Technetium-99 1Taxes 1Ritonavir 1Radiotherapy 1Radionuclide Imaging 1Quality of Life 1Peripheral Blood Stem Cell Transplantation 1Patient Reported Outcome Measures 1Nivolumab 1Molecular Diagnostic Techniques 1Mesna 1Magnetic Resonance Spectroscopy 1Interleukin-12 Subunit p35 1Interleukin-12 1Infracyanine green 1Indocyanine Green 1Indinavir 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Anus Neoplasms × spartalizumab × Breast × Clear all
NCT05941507 2025-09-24

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

LigaChem Biosciences, Inc.

Phase 1/2 Recruiting
300 enrolled
BreastCNSGastrointestinalGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Glioblastoma, Head and Neck Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT04802876 2025-03-21

ACROPOLI

SOLTI Breast Cancer Research Group

Phase 2 Active not recruiting
184 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Adenocarcinoma Of Esophagus, Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Uveal Melanoma, Anus Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasms, Unknown Primary, Sarcoma, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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