Clinical Trials

Phase 3 Active not recruiting

Breast Carcinoma In Situ

NCT02954874 2026-05-15

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

1,155 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05941520 2026-05-13

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

80 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT06184750 2026-05-13

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

200 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT05379153 2026-05-11

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Phase 3 Recruiting

250 enrolled

Breast Carcinoma In Situ

NCT06671912 2026-05-08

LoTam

Phase 3 Suspended

1,156 enrolled

Breast Carcinoma In Situ

NCT04849871 2026-05-06

BreaStBRT

134 enrolled

Phase 2 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms

NCT06008158 2026-05-05

Evaluation of a Once Per Day Regimen of Accelerated Partial Breast Irradiation for Improved Breast Appearance in Pts w/Low Risk, Hormone Responsive Brst Ca

48 enrolled

Phase 1 Active not recruiting

Breast Carcinoma In Situ

NCT03317405 2026-05-04

Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery

32 enrolled 12 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT04245176 2026-05-04

Genetic Testing for All Breast Cancer Patients (GET FACTS)

400 enrolled

Phase 2 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms

NCT01245712 2026-05-01

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

200 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT05755269 2026-05-01

Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women

Terminated

19 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT06538389 2026-04-30

High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer

36 enrolled

Phase 3 Active not recruiting

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT01905046 2026-04-28

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

86 enrolled 10 charts

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT07443943 2026-04-24

AIMSS-RPS

20 enrolled

Breast Carcinoma In Situ

NCT03448926 2026-04-17

PREDICT

Recruiting

3,000 enrolled

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT02928978 2026-04-13

TBCRC042

Phase 2 Completed

84 enrolled

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT05263362 2026-04-13

STARLINGS

Completed

775 enrolled

Phase 1 Not yet recruiting

Breast Carcinoma In Situ, Breast Neoplasms, Fibrosis

NCT07408856 2026-04-08

CAN1012 in Pre-Malignant DCIS and LCIS

24 enrolled

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT04496739 2026-04-07

Making Informed Choices on Incorporating Chemoprevention Into Care (MiCHOICE)

412 enrolled

Breast Carcinoma In Situ

NCT04993313 2026-04-01

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

62 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT05318274 2026-03-23

Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer.

72 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02515110 2026-03-13

Hypofractionated Regional Nodal Irradiation Clinical Trial for Women With Breast Cancer

137 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT03868475 2026-03-09

VAPEX

Phase NA Withdrawn

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating, Cicatrix, Phyllodes Tumor, Patient Satisfaction, Fibroadenoma

NCT03012399 2026-03-05

Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery

50 enrolled

Breast Carcinoma In Situ

NCT03077841 2026-03-05

Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast Cancer

Phase 2/3 Suspended

928 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT05898789 2026-02-25

Virtual Rehabilitation for Cancer Survivors

BreastGastrointestinalHead & NeckLymphoid

388 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Head and Neck Neoplasms, Lymphoma, Lymphoproliferative Disorders, Colorectal Neoplasms

NCT04906200 2026-02-19

YES

400 enrolled

Breast Carcinoma In Situ

NCT03766009 2026-02-11

Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making

627 enrolled 9 charts

Breast Carcinoma In Situ, Breast Neoplasms

NCT05810025 2026-02-11

FHIR

70 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT04368702 2026-02-09

CONFIRM

BreastGastrointestinalGenitourinaryHead & NeckLymphoid

70 enrolled

Breast Carcinoma In Situ, Urinary Bladder Neoplasms, Laryngeal Diseases, Laryngeal Neoplasms, Lymphoma, Stomach Neoplasms, Lymphoma, Mantle-Cell

NCT07042581 2026-02-06

A Study of Revaree Plus in People With Breast Cancer

Phase 4 Recruiting

60 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT04054557 2026-02-05

Patient Reported Outcomes, Smart Pill Bottle and Teleheath for Endocrine Therapy Adherence

305 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT06115486 2026-02-04

EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

30 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma in Situ, Hypertrophy, Motor Activity, Neoplasms

NCT03495011 2026-02-02

MRI Characterization of Mammographically Detected DCIS

Active not recruiting

122 enrolled

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT06335108 2026-01-26

Postoperative Pain After Breast Surgery Under Tumescent Local Anaesthesia Versus General Anaesthesia ( TLA-001 )

Completed

349 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT04570956 2026-01-23

Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk

Phase 2 Terminated

65 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT04959474 2026-01-23

Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

80 enrolled

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating, Triple Negative Breast Neoplasms

NCT04871516 2026-01-22

Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

103 enrolled

Breast Carcinoma In Situ

NCT04754412 2026-01-20

Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study

256 enrolled

Breast Carcinoma In Situ

NCT06234488 2026-01-12

Multi-Institutional Transgender & Gender-Diverse Breast Cancer Study

Active not recruiting

125 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT03345420 2025-12-30

NOVEMBER

Phase 2 Completed

102 enrolled 12 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT04999826 2025-12-30

Multiscale Omics for the Development of a Cohort Database and Study Platform in Breast Cancer Survivors

Completed

105 enrolled

Breast Carcinoma In Situ

NCT06297265 2025-12-18

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

50 enrolled

Breast Carcinoma In Situ

NCT04999917 2025-12-05

BrIMA

206 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT05410951 2025-12-04

LobularCard

Active not recruiting

800 enrolled

Breast Carcinoma In Situ, Carcinoma, Lobular

NCT06153836 2025-12-04

Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction

20 enrolled

Breast Carcinoma In Situ

NCT04074720 2025-12-03

Prospective Breast Cancer Biospecimen Collection

Recruiting

200 enrolled

Phase 2 Enrolling by invitation

Breast Carcinoma In Situ, Breast Neoplasms

NCT06843681 2025-11-28

Trastuzumab Plus Taxane Neoadjuvant Therapy for HER2-Positive Breast Ductal Carcinoma In Situ (DCIS) : A Phase II Study

54 enrolled