Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

INDUSTRY 3

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 10Thoracic 8Head & Neck 4Gynecologic 4Breast 3Genitourinary 2Dermatologic 2

Conditions

Breast Neoplasms 1215Triple Negative Breast Neoplasms 283Ovarian Neoplasms 262Carcinoma, Non-Small-Cell Lung 248Colorectal Neoplasms 189Pancreatic Neoplasms 168Stomach Neoplasms 164Neoplasm Metastasis 156Neoplasms 155Lung Neoplasms 144Prostatic Neoplasms 143Melanoma 132Carcinoma, Renal Cell 103Squamous Cell Carcinoma of Head and Neck 102Endometrial Neoplasms 99Head and Neck Neoplasms 88Colonic Neoplasms 82Urinary Bladder Neoplasms 79Uterine Cervical Neoplasms 77Esophageal Neoplasms 76Sarcoma 71Breast Neoplasms, Male 68Small Cell Lung Carcinoma 66Carcinoma, Hepatocellular 60Carcinoma, Ovarian Epithelial 58Kidney Neoplasms 47Carcinoma, Transitional Cell 41Rectal Neoplasms 35Fallopian Tube Neoplasms 34Liver Neoplasms 32

Interventions

tremelimumab 1durvalumab 1Oxaliplatin 1Leucovorin 1Gemcitabine 1Fluorouracil 1EC regimen 1Cisplatin 1Carboplatin 1CP protocol 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Carcinoma, Pancreatic Ductal × Breast × Clear all
NCT04045496 2025-12-29

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

Jacobio Pharmaceuticals Co., Ltd.

Phase 1 Completed
40 enrolled
BreastGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Noonan Syndrome, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT04121286 2025-05-20

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Allist Pharmaceuticals, Inc.

Phase 1 Completed
17 enrolled
BreastGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Noonan Syndrome, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT02658214 2020-08-20

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

AstraZeneca

Phase 1 Completed
32 enrolled
BreastGastrointestinalGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Carcinoma, Pancreatic Ductal, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

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