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Phase

Phase 2 2Phase 1 2

Status

Completed 3Terminated 1

Sponsor Class

OTHER 48NIH 4OTHER_GOV 3NETWORK 2INDUSTRY 2

Study Type

Interventional 4

Sponsor

Cancer Type

Gynecologic 4Breast 4Genitourinary 2Gastrointestinal 1

Conditions

Breast Neoplasms 513Breast Neoplasms, Male 79Ovarian Neoplasms 54Triple Negative Breast Neoplasms 46Lung Neoplasms 43Colonic Neoplasms 41Prostatic Neoplasms 38Neoplasms 38Neoplasm Metastasis 35Carcinoma, Non-Small-Cell Lung 33Melanoma 31Pancreatic Neoplasms 29Colorectal Neoplasms 28Stomach Neoplasms 24Carcinoma, Ovarian Epithelial 24Endometrial Neoplasms 23Carcinoma, Renal Cell 23Inflammatory Breast Neoplasms 21Brain Neoplasms 20Carcinoma, Intraductal, Noninfiltrating 19Breast Carcinoma In Situ 19Rectal Neoplasms 18Urinary Bladder Neoplasms 17Lymphoma, Non-Hodgkin 17Lymphoma, T-Cell, Cutaneous 16Leukemia, Lymphocytic, Chronic, B-Cell 16Esophageal Neoplasms 16Uterine Cervical Neoplasms 15Precursor Cell Lymphoblastic Leukemia-Lymphoma 15Lymphoma 15

Interventions

veliparib 2Carboplatin 2prexasertib 1Taxes 1Paclitaxel 1Docetaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
NIH × Hereditary Breast and Ovarian Cancer Syndrome × Breast × Clear all
NCT02203513 2022-09-10

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

National Institutes of Health Clinical Center (CC)

Phase 2 Terminated
111 enrolled 15 charts
BreastGenitourinaryGynecologic

Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT00892736 2018-06-29

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

National Cancer Institute (NCI)

Phase 1 Completed
98 enrolled
BreastGastrointestinalGenitourinaryGynecologic

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome, Triple Negative Breast Neoplasms

NCT00535119 2015-05-22

Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer

National Cancer Institute (NCI)

Phase 1 Completed
107 enrolled
BreastGynecologic

Hereditary Breast and Ovarian Cancer Syndrome

NCT00321633 2013-08-26

Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer

National Cancer Institute (NCI)

Phase 2 Completed
148 enrolled
BreastGynecologic

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

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