Clinical Trials

50 enrolled

Breast Neoplasms, Melanoma

NCT07524114 2026-04-13

SHERLOCK

BreastDermatologicGastrointestinalHead & NeckThoracic

7,000 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Unknown Primary, Urogenital Neoplasms, Neoplasm, Residual

NCT05334069 2026-04-07

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

BreastDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

2,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05703269 2026-04-06

HYPOGRYPHE

Phase NA Active not recruiting

58 enrolled

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Small Cell Lung Carcinoma

NCT06500455 2026-04-03

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Phase 3 Recruiting

269 enrolled

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT04890028 2026-03-31

DOPACER

BreastCNSDermatologicThoracic

32 enrolled

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Melanoma

NCT05837767 2026-03-30

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

BreastDermatologicGastrointestinalGenitourinarySarcomaThoracic

26 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Sarcoma, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT04038619 2026-03-20

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

BreastDermatologicGynecologicThoracic

40 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Colitis, Diarrhea, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Urogenital Neoplasms, Uterine Neoplasms

NCT04899908 2026-03-19

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Phase 2 Active not recruiting

134 enrolled

BreastCNSDermatologicGastrointestinalThoracic

Brain Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Phase 1/2 Terminated

8 enrolled 13 charts

BreastCNSDermatologicOther hematologic neoplasmThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT04119024 2026-03-17

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

BreastCNSDermatologicEndocrineHead & NeckNETThoracic

18 enrolled

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Adenoma, Islet Cell, Melanoma, Neoplasm Metastasis, Paraganglioma, Pheochromocytoma, Thyroid Neoplasms, Adrenocortical Carcinoma, Neuroendocrine Tumors

NCT06418204 2026-03-17

COSMIC

BreastDermatologicGastrointestinalLymphoidThoracic

2,000 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Non-Hodgkin, Melanoma, Colorectal Neoplasms

NCT07469709 2026-03-13

PRO-ACTIVE

BreastDermatologicGastrointestinalGynecologicThoracic

850 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Melanoma, Ovarian Neoplasms

NCT05269381 2026-03-12

PNeoVCA

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

132 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05225428 2026-02-25

VERDI

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcoma

1,020 enrolled

Breast Neoplasms, Kidney Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT07406087 2026-02-25

Navigation Intervention for Adolescent and Young Adult Cancer Survivors

Phase NA Not yet recruiting

25 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms

NCT03428581 2026-02-24

Preventing Lymphedema in Axillary Lymph Node Dissection

Phase NA Terminated

264 enrolled

Breast Neoplasms, Lymphedema, Melanoma

NCT04354064 2026-02-20

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

100 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT07042243 2026-02-20

The Florida ASCENT Study

BreastDermatologicGastrointestinalGenitourinaryOther hematologic neoplasmThoracic

100 enrolled

Breast Neoplasms, Feeding Behavior, Food Preferences, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Malnutrition

NCT05488483 2026-02-19

A Study of Tumor Imaging With Multispectral Optoacoustic Tomography

Active not recruiting

12 enrolled

Breast Neoplasms, Melanoma

NCT07410494 2026-02-18

SELECT-CAR-NK

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellThoracic

85 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Liver Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Leukemia, Myeloid, Acute

NCT07410676 2026-02-18

EBNK-ST-001

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT03050268 2026-02-09

SJFAMILY

BreastCNSClassical hematologyDermatologicEndocrineGastrointestinalGynecologicLymphoidOther solid neoplasmSarcoma

1,500 enrolled

Turcot syndrome, Juvenile polyposis syndrome, Choroid Plexus Carcinoma, GATA2 Deficiency, Basal Cell Nevus Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Fanconi Anemia, Hamartoma Syndrome, Multiple, von Hippel-Lindau Disease, Hodgkin Disease, Lymphoma, Non-Hodgkin, Melanoma, Neuroblastoma, Neurofibromatosis 1, Noonan Syndrome, Pancreatic Neoplasms, Paraganglioma, Peutz-Jeghers Syndrome, Pheochromocytoma, Rothmund-Thomson Syndrome, Adenomatous Polyposis Coli, Retinoblastoma, Rhabdomyosarcoma, Tuberous Sclerosis, Neurofibromatosis 2, Li-Fraumeni Syndrome, Adrenocortical Carcinoma, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Dyskeratosis Congenita, Genetic Predisposition to Disease, Anemia, Diamond-Blackfan, Carney Complex, Hereditary Breast and Ovarian Cancer Syndrome

NCT02432963 2026-01-28

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

Phase 1 Active not recruiting

11 enrolled

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Triple Negative Breast Neoplasms

NCT02012699 2026-01-22

iCaRe2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

999,999 enrolled

Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Duodenal Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Lip Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Multiple Myeloma, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Paranasal Sinus Neoplasms, Paraproteinemias, Penile Neoplasms, Peritoneal Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Ureteral Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Central Nervous System Neoplasms, Thyroid Nodule, Endometrial Neoplasms, Neuroendocrine Tumors, Gastrointestinal Stromal Tumors

NCT00508443 2026-01-15

Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)

Phase 1/2 Active not recruiting

150 enrolled

BreastDermatologicGastrointestinalLymphoidSarcomaThoracic

Urogenital Diseases, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Neoplasms, Sarcoma, Spinal Diseases, Spinal Neoplasms

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

Phase 1 Active not recruiting

14 enrolled

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT07310758 2025-12-30

Contrast-enhanced Ultrasound for Sentinel Node Detection

Phase 2/3 Recruiting

91 enrolled

BreastDermatologicHead & Neck

Breast Neoplasms, Head and Neck Neoplasms, Melanoma

NCT07102212 2025-12-24

FOCUS

Phase NA Not yet recruiting

120 enrolled

BreastDermatologicGenitourinaryPlasma cellThoracic

Alzheimer Disease, Anxiety Disorders, Breast Neoplasms, Depression, Fatigue, Lung Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Prostatic Neoplasms

NCT07285044 2025-12-22

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Phase 2 Recruiting

27 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidPlasma cellThoracic

Amyloidosis, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Lymphoma, Mantle-Cell

NCT07260591 2025-12-03

VSV-02 Compassionate Use in Advanced Solid Tumors

BreastDermatologicThoracic

6 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma

NCT03702309 2025-11-26

LIBERATE

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellThoracic

2,500 enrolled

Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Hamartoma Syndrome, Multiple, Head and Neck Neoplasms, Kidney Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Melanoma, Meningioma, Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Neoplasms, Plasma Cell

NCT02639026 2025-11-25

Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers

Phase 1 Completed

53 enrolled

BreastDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT03941756 2025-11-10

Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma

252 enrolled

Melanoma, Inflammatory Breast Neoplasms

NCT06171945 2025-10-27

AYAConnect

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOtherOther hematologic neoplasmSarcoma

63 enrolled

Psychological Well-Being, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Motor Activity, Mouth Neoplasms, Neoplasms, Obesity, Pancreatic Neoplasms, Pharyngeal Neoplasms, Rectal Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Weight Loss, Endometrial Neoplasms, Overweight

NCT06275854 2025-10-14

YASU Research Registry: For Young Adults With Cancer

Terminated

192 enrolled

BreastDermatologicGastrointestinalLymphoidOther hematologic neoplasmSarcoma

Breast Neoplasms, Leukemia, Lymphoma, Melanoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Sarcoma, Colorectal Neoplasms

NCT06180460 2025-10-08

CALM: Managing Distress in Malignant Brain Cancer

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

60 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma

NCT03915678 2025-10-06

AGADIR

Phase 2 Recruiting

247 enrolled

BreastDermatologicGastrointestinalGenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Triple Negative Breast Neoplasms

NCT00722228 2025-10-02

Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

50 enrolled

Breast Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05296564 2025-10-02

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

BreastCNSDermatologicGynecologicSarcomaThoracic

3 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Sarcoma, Synovial, Triple Negative Breast Neoplasms

NCT02831634 2025-09-08

NeoEpitope

25 enrolled

BreastDermatologicGenitourinaryThoracic

Breast Neoplasms, Melanoma

NCT01777802 2025-08-27

SBRT

Completed

98 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms

NCT05057013 2025-08-11

A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours

Phase 1/2 Active not recruiting

81 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Lethal Congenital Contracture Syndrome 2, Fibromatosis, Gingival, 2, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Prostatic Neoplasms, Castration-Resistant, Triple Negative Breast Neoplasms

NCT06384417 2025-08-08

Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2

Phase NA Active not recruiting

32 enrolled

BreastDermatologicGastrointestinalHead & NeckThoracic

Breast Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Phase 1/2 Terminated

19 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04116320 2025-07-14

AM-003

Phase 1 Terminated

5 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma

NCT05196087 2025-07-02

NIP IT!

BreastDermatologicEndocrineGastrointestinalNET

500 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Breast Neoplasms, Melanoma, Neoplasm, Residual

NCT04035447 2025-06-29

Symptom Management for YA Cancer Survivors