Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Withdrawn 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 8Breast 2Gastrointestinal 1

Conditions

Breast Neoplasms 218Triple Negative Breast Neoplasms 17Carcinoma, Intraductal, Noninfiltrating 15Breast Neoplasms, Male 15Inflammatory Breast Neoplasms 13Lung Neoplasms 11Prostatic Neoplasms 10Neoplasms 10Neoplasm Metastasis 10Breast Carcinoma In Situ 9Brain Neoplasms 9Carcinoma, Ductal, Breast 7Melanoma 6Carcinoma, Non-Small-Cell Lung 6Recurrence 5Rectal Neoplasms 4Radiation Injuries 4Lymphoma, Non-Hodgkin 4Lymphoma, Mantle-Cell 4Lymphoma, Large-Cell, Immunoblastic 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Lymphocytic, Chronic, B-Cell 4Hodgkin Disease 4Dendritic Cell Sarcoma, Interdigitating 4Carcinoma, Renal Cell 4Carcinoma, Lobular 4Burkitt Lymphoma 4Testicular Neoplasms 3

Interventions

Magnetic Resonance Spectroscopy 6Spinal Puncture 5Specimen Handling 5Methotrexate 3Trastuzumab 2Radiotherapy, Intensity-Modulated 2Radiotherapy 2trastuzumab deruxtecan 1tipifarnib 1sacituzumab govitecan 1paclitaxel-Angiopep-2 conjugate 1merphos 1eribulin 1epothilone B 1Vinorelbine 1Sorafenib 1Referral and Consultation 1Radiation 1Probability 1Physical Examination 1Pemetrexed 1Immunotherapy, Adoptive 1Immunoenzyme Techniques 1Etoposide 1Cytarabine 1Craniospinal Irradiation 1Cisplatin 1Capecitabine 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Meningeal Carcinomatosis × Radiotherapy × Breast × Clear all
NCT07177950 2025-09-17

A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases

Peking University Cancer Hospital & Institute

Phase 1/2 Not yet recruiting
51 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT06137651 2024-04-01

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Northwestern University

Phase 1 Withdrawn
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

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