Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Breast 2Thoracic 1

Conditions

Breast Neoplasms 543Triple Negative Breast Neoplasms 97Ovarian Neoplasms 58Colorectal Neoplasms 50Prostatic Neoplasms 46Carcinoma, Non-Small-Cell Lung 44Neoplasms 38Lung Neoplasms 33Melanoma 29Endometrial Neoplasms 29Neoplasm Metastasis 28Stomach Neoplasms 26Pancreatic Neoplasms 26Uterine Cervical Neoplasms 25Squamous Cell Carcinoma of Head and Neck 22Colonic Neoplasms 20Head and Neck Neoplasms 18Carcinoma, Renal Cell 18Esophageal Neoplasms 16Sarcoma 14Advanced Breast Cancer 14Small Cell Lung Carcinoma 13Urinary Bladder Neoplasms 12Liver Neoplasms 11Carcinoma, Transitional Cell 11Kidney Neoplasms 10Carcinoma, Intraductal, Noninfiltrating 10Brain Neoplasms 10Lymphedema 9Anatomic Stage I Breast Cancer AJCC v8 9

Interventions

Methotrexate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Meningeal Neoplasms × Breast × 30 days × Clear all
NCT02422641 2026-06-01

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

Wake Forest University Health Sciences

Phase 2 Recruiting
16 enrolled
Breast

Breast Neoplasms, Meningeal Neoplasms

NCT05809752 2026-05-11

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Active not recruiting
15 enrolled
Breast

Meningeal Neoplasms, Triple Negative Breast Neoplasms

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