Clinical Trials

Breast Neoplasms, Neoplasm Metastasis, Neoplasm, Residual

NCT07007559 2026-04-13

ASPEN-09-03

Phase 2 Recruiting

120 enrolled

BreastGastrointestinalGynecologicThoracic

Breast Neoplasms, Neoplasm Metastasis

NCT05143970 2026-03-20

CHANCES

Phase 1 Recruiting

27 enrolled

Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT01613482 2026-03-16

TSARINE

Phase 3 Terminated

13 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT07193394 2026-02-23

H3RAKLES

Phase 2 Recruiting

20 enrolled

Phase 3 Active not recruiting

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT04784715 2026-02-20

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

1,157 enrolled 3 FDA

Phase 1 Active not recruiting

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis

NCT00393783 2025-06-05

Xenogeneic HER2/Neu DNA Immunization for Patients With Metastatic and High Risk Breast Cancer: A Phase I Study to Assess Safety and Immunogenicity

13 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00317720 2025-04-30

Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer

Phase 1/2 Completed

40 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis

NCT04307329 2024-10-22

MIMOSA

12 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT04120246 2024-07-10

Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer

Phase 1 Suspended

24 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01300962 2023-12-04

Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast Cancer

47 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01969643 2023-03-07

A Safety Study of SGN-LIV1A in Breast Cancer Patients

290 enrolled

Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT00807859 2022-11-08

Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer

65 enrolled

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00810017 2022-05-19

Phase 2 Study of Trastuzumab and Etoposide for Her2 Positive Breast Cancer

Phase 2 Terminated

2 enrolled 3 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00297596 2021-10-28

Trastuzumab and Oxaliplatin in Patients With Metastatic Breast Cancer

25 enrolled 6 charts

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Breast Neoplasms, Neoplasm Metastasis

NCT04464967 2021-05-12

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Phase 1/2 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Recurrence, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT01835236 2021-03-30

Trastuzumab & Pertuzumab Followed by T-DM1 in MBC

208 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT02139358 2021-02-04

Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer

Phase 1/2 Completed

15 enrolled 12 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01387373 2020-10-05

Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Breast Cancer

14 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00367471 2020-09-09

Combination Of Lapatinib With Carboplatin, Paclitaxel, and With or Without Trastuzumab In Metastatic Breast Cancer.

31 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00140140 2019-11-26

A Phase I/II Study of ABI-007 (Abraxane®, Nab®-Paclitaxel)and Vinorelbine in Patients With Stage IV (Metastatic) Breast Cancer

Phase 1/2 Terminated

16 enrolled 21 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00876395 2018-12-19

BOLERO-1

Phase 3 Completed

719 enrolled 25 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00428922 2018-08-09

Trastuzumab (Herceptin), Bevacizumab, and Docetaxel (Taxotere) Trial in Stage IV Metastatic Breast Cancer (MBC) Patients

26 enrolled 5 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00201760 2017-12-27

Gemcitabine/ Trastuzumab and Gemcitabine/ Cisplatin/ Trastuzumab in Patients With Metastatic Breast Cancer

10 enrolled 9 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01512199 2017-10-18

Phase 1b/2 Study of U3-1287 in Combination With Trastuzumab Plus Paclitaxel in Newly Diagnosed Metastatic Breast Cancer (MBC)

Phase 1/2 Terminated

29 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01304797 2017-01-06

Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer

Phase 1 Unknown

75 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT02238509 2016-06-15

Safety and QoL of Trastuzumab With Lapatinib or Chemiotherapy in MBC and HER2+ Patients Refractory to Anti HER2 Therapies

Phase 2 Unknown

154 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01048099 2016-01-29

Use of PRO Onc Assay to Assess HER2 in Patients With Metastatic Breast Cancer

Phase NA Completed

283 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01985893 2016-01-14

THOR

Phase 2 Withdrawn

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00426556 2015-12-28

Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

88 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00377780 2015-09-23

MYOHERTAX

Phase 2 Terminated

60 enrolled

Breast Neoplasms, Neoplasm Metastasis, Cardiotoxicity

NCT01242449 2015-05-21

OVINTRA

10 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00301730 2015-04-28

Cellular Adoptive Immunotherapy in Treating a Patient Who Has Undergone a Donor Stem Cell Transplant for Breast Cancer That Has Spread to the Lung

1 enrolled

BreastCNSDermatologicThoracic

Breast Neoplasms, Neoplasm Metastasis

NCT01386580 2015-01-22

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

Phase 1/2 Completed

84 enrolled

Brain Diseases, Brain Neoplasms, Breast Neoplasms, Central Nervous System Diseases, Glioma, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Nervous System Diseases, Nervous System Neoplasms, Pathologic Processes, Central Nervous System Neoplasms

NCT00398437 2013-08-12

Magnetic Resonance Imaging for the Early Detection of CNS Metastases in Women With Stage IV Breast Cancer

Phase NA Unknown

96 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT00795678 2013-08-02

Chemotherapeutic Agents in Brain/Breast

Completed

10 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT00171847 2010-03-31

eLEcTRA

Phase 4 Terminated

93 enrolled