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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 8Thoracic 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Breast Neoplasms 111Triple Negative Breast Neoplasms 25Lung Neoplasms 8Pancreatic Neoplasms 6Neoplasm Metastasis 6Colonic Neoplasms 6Ovarian Neoplasms 5Neoplasms 5Melanoma 5Colorectal Neoplasms 5Stomach Neoplasms 4Head and Neck Neoplasms 4Esophageal Neoplasms 4Sarcoma 3Liver Neoplasms 3Kidney Neoplasms 3Cholangiocarcinoma 3Uterine Cervical Neoplasms 2Multiple Myeloma 2Motor Activity 2Lymphoma, Non-Hodgkin 2Lymphoma 2Laryngeal Neoplasms 2Gastrointestinal Neoplasms 2Fatigue 2Fallopian Tube Neoplasms 2Carcinoma, Renal Cell 2Carcinoma, Non-Small-Cell Lung 2Brain Neoplasms 2Bile Duct Neoplasms 2

Interventions

pembrolizumab 2Fluorodeoxyglucose F18 2motexafin gadolinium 1fluoromisonidazole 1Vorinostat 1Taxes 1Rubidium-82 1Ritonavir 1Radiotherapy 1Polymerase Chain Reaction 1Nivolumab 1Magnetic Resonance Spectroscopy 1Indinavir 1Immunohistochemistry 1Gene Expression Profiling 1Fluorescent Antibody Technique 1Flow Cytometry 1FPP(RGD)2 1Drug Therapy 1Doxorubicin 1Biopsy 15-fluoropentyl-2-methylmalonic acid 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Drug Therapy × Breast × Clear all
NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Celldex Therapeutics

Phase 1 Completed
132 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

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