Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Head & Neck 1Gynecologic 1Endocrine 1Breast 1

Conditions

Breast Neoplasms 20Triple Negative Breast Neoplasms 14Ovarian Neoplasms 7Melanoma 7Carcinoma, Non-Small-Cell Lung 6Neoplasms 5Neoplasm Metastasis 5Carcinoma, Renal Cell 5Stomach Neoplasms 4Pancreatic Neoplasms 4Head and Neck Neoplasms 4Carcinoma, Transitional Cell 4Uterine Cervical Neoplasms 3Squamous Cell Carcinoma of Head and Neck 3Small Cell Lung Carcinoma 3Sarcoma 3Endometrial Neoplasms 3Carcinoma, Hepatocellular 3Prostatic Neoplasms 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Multiple Myeloma 2Mesothelioma 2Lymphoma, Non-Hodgkin 2Lymphoma 2Lung Neoplasms 2Liver Neoplasms 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Leukemia, Myeloid, Acute 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Leukemia, Lymphocytic, Chronic, B-Cell 2

Interventions

Trastuzumab 2vandetanib 1tipifarnib 1spartalizumab 1fludarabine 1aldesleukin 1Nivolumab 1Ipilimumab 1Interleukin-12 Subunit p35 1Interleukin-12 1Docetaxel 1Cyclophosphamide 1CTLA-4 Antigen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Thyroid Carcinoma, Anaplastic × Ipilimumab × Breast × Clear all
NCT03449108 2026-05-22

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
30 enrolled
BreastEndocrineGynecologicHead & NeckSarcoma

Bone Neoplasms, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Giant Cell Tumor of Bone, Histiocytoma, Malignant Fibrous, Triple Negative Breast Neoplasms, Thyroid Carcinoma, Anaplastic

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