Announcements Trials
Browse Landscape

Phase

Phase 1 4Phase 2 1

Status

Terminated 5Completed 5Withdrawn 1Recruiting 1

Sponsor Class

NIH 4INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 6Breast 5Other hematologic neoplasm 4Lymphoid 4Tumor-Agnostic 3Thoracic 3Head & Neck 3Gynecologic 3Other solid neoplasm 2Sarcoma 1NET 1Myeloid 1Endocrine 1Dermatologic 1CNS 1

Conditions

Breast Neoplasms 5Ovarian Neoplasms 1Glioblastoma 1Breast Neoplasms, Male 1

Interventions

Trastuzumab 379Paclitaxel 369Cyclophosphamide 338Docetaxel 314Capecitabine 198Doxorubicin 196Letrozole 184Tamoxifen 154Carboplatin 153Fulvestrant 136Bevacizumab 129Anastrozole 120exemestane 119Lapatinib 117Epirubicin 116Gemcitabine 112Radiotherapy 107palbociclib 94Exercise 87Fluorouracil 83Vinorelbine 82Surveys and Questionnaires 81pertuzumab 77Albumin-Bound Paclitaxel 76Filgrastim 71130-nm albumin-bound paclitaxel 64pembrolizumab 63Everolimus 59Cisplatin 59eribulin 58

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × MK 2206 × Breast × Clear all
NCT01277757 2018-12-19

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

National Cancer Institute (NCI)

Phase 2 Completed
30 enrolled 7 charts
Breast

Breast Neoplasms

NCT01344031 2018-07-23

MK2206 in Combination With Anastrozole, Fulvestrant, or Anastrozole and Fulvestrant in Treating Postmenopausal Women With Metastatic Breast Cancer

National Cancer Institute (NCI)

Phase 1 Completed
31 enrolled
Breast

Breast Neoplasms

NCT01263145 2017-08-25

MK2206 and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Metastatic Breast Cancer

National Cancer Institute (NCI)

Phase 1 Completed
34 enrolled
Breast

Breast Neoplasms

NCT01295632 2015-08-27

Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)

Merck Sharp & Dohme LLC

Phase 1 Completed
65 enrolled
BreastCNSGynecologic

Breast Neoplasms, Glioblastoma, Ovarian Neoplasms

NCT01245205 2014-10-23

Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast Cancer

National Cancer Institute (NCI)

Phase 1 Completed
28 enrolled
Breast

Breast Neoplasms, Breast Neoplasms, Male

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