Announcements Trials
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Phase

Phase 2 5Phase NA 1

Status

Completed 25Unknown 12Terminated 6Recruiting 3Active not recruiting 3Withdrawn 2

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

Genitourinary 10Gastrointestinal 9Thoracic 8Breast 6Lymphoid 3Head & Neck 3Sarcoma 2Other hematologic neoplasm 2CNS 2Tumor-Agnostic 1Other 1Dermatologic 1

Conditions

Breast Neoplasms 6Neoplasms 1Cardiotoxicity 1

Interventions

Trastuzumab 87Cyclophosphamide 67Capecitabine 67Paclitaxel 64Docetaxel 58Fulvestrant 52Letrozole 50Carboplatin 42pembrolizumab 41Lapatinib 38Doxorubicin 36Anastrozole 32Vinorelbine 31Bevacizumab 31exemestane 28Tamoxifen 25Gemcitabine 25Albumin-Bound Paclitaxel 25Radiotherapy 21Taxes 19atezolizumab 18pertuzumab 17Everolimus 17130-nm albumin-bound paclitaxel 17Epirubicin 16palbociclib 15Magnetic Resonance Spectroscopy 15eribulin 14Ado-Trastuzumab Emtansine 14Goserelin 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Terminated × Metformin × Breast × Clear all
NCT02874430 2026-04-22

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Thomas Jefferson University

Phase 2 Terminated
29 enrolled 11 charts
Breast

Breast Neoplasms

NCT00984490 2024-02-01

Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

Vanderbilt-Ingram Cancer Center

Phase NA Terminated
5 enrolled 4 charts
Breast

Breast Neoplasms

NCT01627067 2020-06-19

Exemestane-RAD001-Metformin

M.D. Anderson Cancer Center

Phase 2 Terminated
23 enrolled 7 charts
Breast

Breast Neoplasms

NCT02472353 2019-10-16

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Avera McKennan Hospital & University Health Center

Phase 2 Terminated
30 enrolled 10 charts
Breast

Breast Neoplasms, Neoplasms, Cardiotoxicity

NCT02360059 2017-08-17

Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer

M.D. Anderson Cancer Center

Phase 2 Terminated
1 enrolled 3 charts
Breast

Breast Neoplasms

NCT01477060 2014-02-20

Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer

Fondazione Michelangelo

Phase 2 Terminated
32 enrolled
Breast

Breast Neoplasms

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