Clinical Trials

Phase 3 Active not recruiting

Breast Neoplasms

NCT00310180 2026-04-13

TAILORx

10,273 enrolled 14 charts

Phase 3 Active not recruiting

Breast Neoplasms

NCT02954874 2026-04-13

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

1,155 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03598257 2026-04-13

Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer

300 enrolled

Phase 1 Active not recruiting

Inflammatory Breast Neoplasms

NCT04052555 2026-04-13

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

42 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05406232 2026-04-09

Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer

Recruiting

20 enrolled

Breast Neoplasms

NCT04266249 2026-03-23

CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

2,175 enrolled

Anatomic Stage II Breast Cancer AJCC v8

NCT01266642 2026-03-11

Hypofractionated Radiation Therapy or Standard Radiation Therapy in Treating Patients With Ductal Breast Carcinoma In Situ or Early Invasive Breast Cancer

301 enrolled 9 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT03359954 2026-03-05

Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer

25 enrolled

Estrogen Receptor Positive

NCT02927912 2026-02-17

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

108 enrolled

Breast Neoplasms

NCT04683679 2026-02-17

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

Phase 2 Recruiting

34 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07188246 2026-02-11

BRINK

Phase 2 Recruiting

40 enrolled

Phase 1/2 Active not recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

125 enrolled

BreastCNSDermatologicGenitourinary

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT00066690 2026-02-06

SOFT

Phase 3 Completed

3,066 enrolled 15 charts

Breast Neoplasms

NCT02912312 2026-01-07

Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer

805 enrolled

Phase 1 Active not recruiting

Breast Neoplasms

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

14 enrolled

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT02352883 2025-12-19

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

Phase NA Active not recruiting

368 enrolled

Phase 2 Not yet recruiting

Carcinoma, Intraductal, Noninfiltrating

NCT06492759 2025-12-16

High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

29 enrolled

Triple Negative Breast Neoplasms

NCT06635980 2025-12-12

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

Phase 2 Recruiting

120 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01750073 2025-11-18

Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer

92 enrolled 17 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07037576 2025-06-25

Efficacy and Safety of Prepectoral Prosthesis Immediate One-Stage Breast Reconstruction Versus Two-Stage Expander/Prosthesis Reconstruction in Postoperative Adjuvant Radiotherapy Breast Cancer Patients: A Prospective, Single-Center, Cohort Study

Recruiting

104 enrolled

Breast Neoplasms

NCT01819233 2025-06-06

CAREFOR

38 enrolled 10 charts

Phase 1/2 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT00838929 2025-05-04

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

Phase 1 Completed

17 enrolled 8 charts

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT02917421 2025-05-04

ART

88 enrolled 10 charts

Breast Neoplasms

NCT06847555 2025-02-26

Phase I-II Clinical Study of Taurine for External Use in the Prevention and Treatment of Acute Radiation Skin Injury

Phase 1/2 Recruiting

24 enrolled

To Evaluate the Safety of Taurine in Preventing Acute Radiation Skin Injury Induced by Adjuvant Radiotherapy in Breast Cancer Patients

NCT03691493 2025-02-17

ASPIRE

Phase 2 Completed

36 enrolled 17 charts

Breast Neoplasms

NCT01618357 2024-05-22

Pre-Operative Radiation and Veliparib for Breast Cancer

Phase 1 Completed

19 enrolled

Breast Neoplasms

NCT03324802 2024-05-02

Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery

Phase 3 Completed

107 enrolled 17 charts

Breast Neoplasms

NCT06137651 2024-04-01

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Phase 1 Withdrawn

BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT03677427 2024-03-05

YO-HAI5

488 enrolled

BreastHead & NeckLymphoid

Breast Neoplasms

NCT03789097 2024-01-30

Vaccination With Flt3L, Radiation, and Poly-ICLC

Phase 1/2 Unknown

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Lymphoma, Lymphoma, Non-Hodgkin

NCT04756505 2023-12-27

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

Phase 1 Withdrawn

Breast Neoplasms

NCT04690855 2023-12-04

TARA

Phase 2 Terminated

1 enrolled 11 charts

BreastDermatologicLymphoidSarcoma

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT02890368 2023-04-05

Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides

Phase 1 Terminated

56 enrolled

Breast Neoplasms, Carcinoma, Squamous Cell, Melanoma, Mycosis Fungoides, Sarcoma, Carcinoma, Merkel Cell

NCT00470236 2023-03-22

DCIS

Phase NA Unknown

1,608 enrolled

Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast

NCT03437161 2023-02-17

A Prospective Trial to Compare Deep Inspiratory Breath Hold (DIBH) With Prone Breast Irradiation

40 enrolled

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Deception

NCT00887523 2022-12-20

Trial Comparing Prone and Supine Intensity-modulated Radiotherapy (IMRT) After Breast-conserving Surgery in Patients With Large Breast Volume at High Risk for Skin Toxicity and Fibrosis

100 enrolled

Breast Neoplasms

NCT02335957 2022-04-01

OPTIMAL

489 enrolled

NCT03524170 2022-03-07

Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

Phase 1 Completed

24 enrolled

Breast Neoplasms

NCT01727011 2021-12-17

SIFEBI

37 enrolled 7 charts

Breast Neoplasms

NCT01421017 2021-11-18

Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases

Phase 1/2 Completed

31 enrolled 11 charts

Breast Neoplasms

NCT03972696 2021-11-01

OPTIMALIIa

Phase NA Terminated

32 enrolled

Breast Neoplasms

NCT04488614 2020-07-30

PBCB

Enrolling by invitation

1,200 enrolled

Breast Neoplasms, Fatigue

NCT00278109 2020-02-19

Partial Breast Irradiation With Chemotherapy

Phase 1/2 Completed

27 enrolled 5 charts

Breast Neoplasms

NCT02538471 2019-12-09

LY2157299 Monohydrate (LY2157299) and Radiotherapy in Metastatic Breast Cancer

Phase 2 Terminated

3 enrolled 11 charts

Breast Neoplasms

NCT00418210 2019-12-05

Accelerated Partial Breast Irradiation for Early Breast Cancer

48 enrolled

Breast Neoplasms

NCT03935802 2019-05-02

Analysis of Circulating Epithelial Tumor Cells in Peripheral Blood in Patients With Primary Non-metastatic Breast Cancer Under Adjuvant Radiotherapy

Completed

161 enrolled

Breast Neoplasms

NCT02890316 2019-04-09

Assessment of Fatigue During Radiotherapy for Breast Cancer With and Without Homeopathy Treatment

64 enrolled

Breast Neoplasms

NCT01091883 2019-03-13

Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma