Clinical Trials Browser

Radiotherapy × Breast × Clear all

NCT07578116 2026-05-27

Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis

Phase 3 Not yet recruiting

Anatomic Stage IV Breast Cancer AJCC v8

NCT00310180 2026-05-26

TAILORx

Phase 3 Active not recruiting

10,273 enrolled 14 charts

Breast Neoplasms

NCT04648904 2026-05-26

Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer

Phase EARLY_PHASE1 Active not recruiting

Invasive Breast Cancer

NCT02954874 2026-05-15

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Phase 3 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07053085 2026-05-14

A Study of Surgery and Radiotherapy in People With Breast Cancer

Phase 2 Recruiting

Breast Neoplasms

NCT03598257 2026-05-13

Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer

Phase 2 Active not recruiting

Inflammatory Breast Neoplasms

NCT04052555 2026-05-13

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

Phase 1 Active not recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05464667 2026-05-08

Preoperative Irradiation for Stage I Breast Cancer

Phase NA Active not recruiting

Breast Neoplasms

NCT04175210 2026-05-07

PRART

Phase 3 Active not recruiting

397 enrolled 9 charts

Breast Neoplasms

NCT06129747 2026-05-07

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Phase 2 Recruiting

Breast Neoplasms, Neoplasms

NCT05406232 2026-05-06

Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer

Breast Neoplasms

NCT04266249 2026-05-05

CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

Phase 2 Active not recruiting

Anatomic Stage II Breast Cancer AJCC v8

NCT02700386 2026-04-30

Shorter Course Radiation for the Treatment of Breast Cancer That Has Spread to Lymph Nodes

Phase 2 Completed

108 enrolled 14 charts

Breast Neoplasms, Neoplasms

NCT07554573 2026-04-28

ABCD RT

Phase 3 Not yet recruiting

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00872625 2026-04-23

Radiation Therapy and Docetaxel Followed by Standard Therapy in Treating Women With Breast Cancer

Phase 1 Completed

Breast Neoplasms

NCT05491226 2026-04-20

Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation

Phase 2 Recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07015853 2026-04-20

ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation

Phase 2 Not yet recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT06492759 2026-04-17

High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

Phase 2 Recruiting

Triple Negative Breast Neoplasms

NCT05607017 2026-04-06

Losartan in Prevention of Radiation-Induced Heart Failure

Phase EARLY_PHASE1 Completed

Radiation Fibrosis Syndrome, Breast Neoplasms

NCT01570998 2026-03-18

Intraoperative Radiation Therapy in Treating Patients With Breast Cancer Undergoing Breast-Conserving Surgery

Phase NA Active not recruiting

Breast Neoplasms

NCT04454528 2026-03-10

BreastVAX

Phase 1/2 Active not recruiting

Breast Neoplasms

NCT06954623 2026-03-10

BREAST

Phase NA Recruiting

Breast Neoplasms

NCT06704659 2026-03-09

RAY-no-BAN

Phase NA Recruiting

Breast Neoplasms, Recurrence

NCT03359954 2026-03-05

Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer

Phase 2 Active not recruiting

Estrogen Receptor Positive

NCT04075305 2026-03-05

MOMENTUM

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms

NCT03414970 2026-02-24

Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

Phase 3 Active not recruiting

898 enrolled 13 charts

Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT02927912 2026-02-17

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

Phase 2 Active not recruiting

Breast Neoplasms

NCT07217990 2026-02-17

NoCUT-BC

Phase 1/2 Not yet recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT06678269 2026-02-12

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

Phase 1 Recruiting

Breast Neoplasms

NCT06135714 2026-02-11

OLIGAMI

Phase 3 Recruiting

Breast Neoplasms

NCT05415215 2026-02-10

ProHer

Phase 3 Completed

346 enrolled 20 charts

Breast Neoplasms, Patient Preference, Inflammatory Breast Neoplasms

NCT00066690 2026-02-06

SOFT

Phase 3 Completed

3,066 enrolled 15 charts

Breast Neoplasms

NCT01796197 2026-02-05

Paclitaxel + Trastuzumab + Pertuzumab as Pre-Op for Inflammatory BrCa

Phase 2 Completed

23 enrolled 10 charts

Breast Neoplasms

NCT02492607 2026-01-26

LORD

Phase NA Active not recruiting

Carcinoma, Intraductal, Noninfiltrating

NCT03878342 2026-01-23

ROMANCE

Phase NA Active not recruiting

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00508443 2026-01-15

Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)

Phase 1/2 Active not recruiting

BreastDermatologicGastrointestinalLymphoidSarcomaThoracic

Urogenital Diseases, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Neoplasms, Sarcoma, Spinal Diseases, Spinal Neoplasms

NCT07344597 2026-01-15

Prospective Comparative Study of Hypofractionated Adjuvant Radiotherapy in 2 Virsus 3 Weeks in Breast Cancer

Not yet recruiting

Breast Neoplasms

NCT06747065 2026-01-14

PRExRT

Breast Neoplasms, Lymphedema

NCT01413269 2026-01-12

Randomized Study of Hypofractionated and Conventional Fractionation Radiotherapy After Breast Conservative Surgery

Phase 3 Completed

Breast Neoplasms

NCT02912312 2026-01-07

Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer

Phase 2 Active not recruiting

Breast Neoplasms

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

Phase 1 Active not recruiting

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT02352883 2025-12-19

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

Phase NA Active not recruiting

Carcinoma, Intraductal, Noninfiltrating

NCT06297265 2025-12-18

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

Phase NA Recruiting

Breast Carcinoma In Situ

NCT00929214 2025-12-17

Aggressive Local Therapy for Limited Bone-Only Metastasis to Improve Progression-Free Survival in Breast Cancer Patients

Phase 2 Active not recruiting

Breast Neoplasms, Neoplasm Metastasis

NCT06961955 2025-12-09

FAST NOVEMBER

Phase 2 Recruiting

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT03542175 2025-12-08

A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy

Phase 1 Completed

31 enrolled 12 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT02639026 2025-11-25

Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers

Phase 1 Completed

BreastDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT03109080 2025-11-24

RadioPARP

Phase 1 Completed

Radiation Injuries, Triple Negative Breast Neoplasms

NCT01750073 2025-11-18

Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer

Phase 2 Active not recruiting

92 enrolled 17 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT06295744 2025-10-23

Outcomes and Cosmesis With Whole Breast Irradiation and Boost

Phase NA Recruiting

Breast Neoplasms