Announcements Trials
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Phase

Phase 1 5Phase 2 1Phase 1/2 1

Status

Terminated 2Completed 2Withdrawn 1

Sponsor Class

OTHER 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 5Tumor-Agnostic 2Other solid neoplasm 1Gynecologic 1Gastrointestinal 1

Conditions

Breast Neoplasms 3Triple Negative Breast Neoplasms 2Anatomic Stage II Breast Cancer AJCC v8 1

Interventions

Paclitaxel 100Trastuzumab 81pembrolizumab 78Fulvestrant 68Cyclophosphamide 66Carboplatin 49Capecitabine 47Docetaxel 45palbociclib 41Lapatinib 40Letrozole 37Doxorubicin 29olaparib 28Taxes 28Nivolumab 25Magnetic Resonance Spectroscopy 25Gemcitabine 25130-nm albumin-bound paclitaxel 25Everolimus 23Biopsy 23ribociclib 22abemaciclib 21Specimen Handling 21Albumin-Bound Paclitaxel 21Cisplatin 20Radiotherapy 19Bevacizumab 19Ado-Trastuzumab Emtansine 19pertuzumab 17Alpelisib 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × bintrafusp alfa protein, human × Breast × Clear all
NCT03620201 2024-10-22

M7824 in Treating Patients With Stage II-III HER2 Positive Breast Cancer

M.D. Anderson Cancer Center

Phase 1 Completed
20 enrolled
Breast

Anatomic Stage II Breast Cancer AJCC v8

NCT04756505 2023-12-27

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

M.D. Anderson Cancer Center

Phase 1 Withdrawn
Breast

Breast Neoplasms

NCT03579472 2022-10-31

M7824 and Eribulin Mesylate in Treating Patients With Metastatic Triple Negative Breast Cancer

M.D. Anderson Cancer Center

Phase 1 Terminated
38 enrolled
Breast

Triple Negative Breast Neoplasms

NCT03524170 2022-03-07

Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

M.D. Anderson Cancer Center

Phase 1 Completed
24 enrolled
Breast

Breast Neoplasms

NCT04296942 2022-01-11

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
1 enrolled 10 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

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