Announcements Trials
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Phase

Phase 1 3Phase NA 1Phase 3 1

Status

Completed 3Withdrawn 1Terminated 1

Sponsor Class

OTHER 3NIH 1NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 3Lymphoid 1

Conditions

Brain Neoplasms 129Neoplasm Metastasis 33Glioblastoma 24Melanoma 22Lung Neoplasms 16Carcinoma, Non-Small-Cell Lung 16Breast Neoplasms 15Glioma 12Small Cell Lung Carcinoma 8Neoplasms 8Gliosarcoma 8Central Nervous System Neoplasms 7Neuroma, Acoustic 6Meningioma 6Carcinoma, Renal Cell 6Astrocytoma 5Spinal Cord Neoplasms 4Recurrence 4Sarcoma 3Oligodendroglioma 3Gastrointestinal Neoplasms 3Breast Neoplasms, Male 3Uveal Melanoma 2Radiation Injuries 2Prostatic Neoplasms 2Kidney Neoplasms 2Fatigue 2Depression 2Colorectal Neoplasms 2Anxiety Disorders 2

Interventions

Temozolomide 115Radiotherapy 63Magnetic Resonance Spectroscopy 30Carboplatin 30Bevacizumab 30Carmustine 28Filgrastim 23Surgical Procedures, Operative 22Irinotecan 22Radiation 18Lomustine 17Vincristine 15Etoposide 15Specimen Handling 13Peripheral Blood Stem Cell Transplantation 13O(6)-benzylguanine 13Radiotherapy, Intensity-Modulated 12Procarbazine 11Erlotinib Hydrochloride 11Cyclophosphamide 11Chemotherapy, Adjuvant 11sargramostim 10Thiotepa 10Cisplatin 10Flucytosine 9Everolimus 9antineoplaston AS 2-1 8antineoplaston A10 8Granulocyte Colony-Stimulating Factor 8Vorinostat 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Astrocytoma × Radiosurgery × CNS × Clear all
NCT02186509 2025-04-30

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Thomas Jefferson University

Phase 1 Completed
17 enrolled 11 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT03956706 2023-03-15

Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas

Northwell Health

Phase NA Withdrawn
CNSLymphoid

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular

NCT01392209 2019-11-22

Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
15 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01378481 2014-12-23

High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

National Cancer Institute (NCI)

Phase 1 Terminated
30 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00003916 2012-09-24

Standard Radiation Therapy With or Without Stereotactic Radiation Therapy in Treating Patients With Glioma

European Organisation for Research and Treatment of Cancer - EORTC

Phase 3 Completed
25 enrolled
CNSSarcoma

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

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