Clinical Trials Browser

Brain Neoplasms × Surgical Procedures, Operative × CNS × Clear all

NCT02792582 2026-04-17

A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection

Phase 2 Active not recruiting

Brain Neoplasms, Craniopharyngioma

NCT07053033 2026-03-09

Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)

Phase 2 Recruiting

Brain Neoplasms

NCT07384884 2026-02-19

SLITT-GBM

Phase NA Not yet recruiting

Brain Neoplasms

NCT07197632 2025-09-29

MET-MRI

Phase NA Recruiting

Brain Neoplasms

NCT02981940 2025-09-02

A Study of Abemaciclib in Recurrent Glioblastoma

Phase 2 Active not recruiting

45 enrolled 10 charts

Brain Neoplasms, Glioblastoma

NCT02507583 2025-05-07

Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma

Phase 1 Completed

Brain Neoplasms, Glioma, Neoplasms

NCT05616377 2022-11-15

CLTBME

Brain Neoplasms

NCT01567202 2020-09-09

Study of DC Vaccination Against Glioblastoma

Phase 2 Unknown

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00003320 2020-08-03

Radiation Therapy Following Surgery to Remove Brain Metastases

Phase NA Completed

Brain Neoplasms, Neoplasm Metastasis

NCT00047073 2020-08-03

Sirolimus in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT04358666 2020-04-24

OPTMETACER

Phase NA Unknown

Brain Neoplasms

NCT03910556 2019-04-12

Re-craniotomy and Complications After Elective Neurosurgery

Brain Neoplasms

NCT01339052 2019-03-19

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

Phase 2 Completed

65 enrolled 30 charts

Brain Neoplasms, Glioblastoma

NCT01644955 2018-07-02

Carboplatin in Treating Patients With Recurrent High-Grade Gliomas

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma

NCT00837928 2018-05-17

Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors

Phase 1 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT00030628 2016-07-07

Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT01213407 2016-05-19

GBM-Vax

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT00003484 2015-04-23

Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003461 2014-08-21

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors

Phase 1/2 Completed

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00238303 2014-05-23

Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Phase 2 Completed

103 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01169129 2014-02-04

Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases

Phase 3 Withdrawn

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00003842 2013-12-18

IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002708 2013-11-19

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT00003788 2013-11-06

Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas

Phase 3 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003876 2013-06-26

Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003574 2013-06-21

Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003467 2013-06-20

Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01295970 2013-06-13

Surgery Versus Radiosurgery for the Treatment of Single Brain Metastases

Phase NA Withdrawn

Brain Neoplasms

NCT00004024 2013-04-05

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00003463 2013-02-18

Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00460395 2012-02-24

Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial

Phase 3 Completed

Brain Neoplasms

NCT00089427 2011-07-04

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00064779 2011-06-06

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00076986 2011-06-06

The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme

Phase 3 Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT00124761 2010-09-06

A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis