Clinical Trials

16 enrolled

CNSSarcoma

Brain Neoplasms, Neuroblastoma, Sarcoma

NCT02259218 2026-04-13

Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy

273 enrolled

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Radiation Injuries

NCT03115398 2026-04-13

A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery

CNSGastrointestinalGynecologicHead & NeckThoracic

166 enrolled

Brain Neoplasms, Uterine Cervical Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT04988750 2026-04-13

Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients

7 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT04446416 2026-04-09

Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients

6 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue

NCT02153957 2026-04-08

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

36 enrolled

Brain Neoplasms, Motor Activity

NCT02595905 2026-04-08

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

Phase EARLY_PHASE1 Completed

344 enrolled 11 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05704933 2026-04-06

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

1 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT00850278 2026-04-02

FLT

50 enrolled

Brain Neoplasms, Neoplasms

NCT01445483 2026-03-31

Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases

35 enrolled

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT04890028 2026-03-31

DOPACER

BreastCNSDermatologicThoracic

32 enrolled

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Melanoma

NCT03194971 2026-03-30

NovoTTF Treatment Signatures in Glioblastoma Patients at Autopsy

20 enrolled

Brain Neoplasms, Glioblastoma

NCT07499141 2026-03-30

UFGAG

41 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT02851706 2026-03-27

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

1,214 enrolled

Astrocytoma, Brain Neoplasms, Glioma, Neoplasms, Spinal Cord Neoplasms

NCT04266665 2026-03-25

Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

Phase 4 Completed

56 enrolled

Neuroinflammatory Diseases, Hypoxia, Brain Neoplasms

NCT03251989 2026-03-24

Rare CNS Tumors Outcomes &Risk

326 enrolled

Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT04545814 2026-03-24

Analyzing Preoperative Stereotactic Radiosurgery With Gamma Knife Icon for Brain Metastases

11 enrolled 11 charts

Brain Neoplasms

NCT03714243 2026-03-20

BBBD

8 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT03475186 2026-03-13

Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

75 enrolled 47 charts

Brain Neoplasms, Glioblastoma, Cognitive Dysfunction

NCT04044937 2026-03-11

UC-GlioFET

143 enrolled

Brain Neoplasms, Glioblastoma

NCT04301089 2026-03-11

Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients

61 enrolled 20 charts

Anxiety Disorders, Brain Neoplasms

NCT02858869 2026-03-09

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

25 enrolled 14 charts

CNSDermatologicThoracic

Uveal Melanoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT02303678 2026-03-06

D2C7 for Adult Patients With Recurrent Malignant Glioma

81 enrolled

Brain Neoplasms, Glioma

NCT03368625 2026-03-04

NASRS

30 enrolled

Brain Neoplasms

NCT03719768 2026-03-02

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

16 enrolled

Brain Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT04238819 2026-03-02

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Phase 1/2 Completed

47 enrolled 36 charts

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT02669173 2026-02-23

Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma

12 enrolled

Brain Neoplasms, Glioblastoma, Recurrence

NCT04268979 2026-02-20

Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator

296 enrolled 11 charts

Brain Neoplasms

NCT05984667 2026-02-20

C-SMART

32 enrolled

Brain Neoplasms, Glioma, Neurocognitive Disorders

NCT07405047 2026-02-12

Fractionated Stereotactic Radiotherapy for Limited Small Volume Brain Metastases

33 enrolled

Brain Neoplasms

NCT02909777 2026-02-11

Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma

Phase EARLY_PHASE1 Completed

26 enrolled

CNSLymphoid

Brain Neoplasms, Lymphoma, Neuroblastoma

NCT04173104 2026-02-09

PET and MRI Imaging of Brain Tumors Using [18F]PARPi

5 enrolled

Brain Neoplasms

NCT03361033 2026-02-05

Components of Social Functioning in Survivors of Pediatric Brain Tumors

80 enrolled

Brain Neoplasms, Medulloblastoma, Social Adjustment

NCT05427838 2026-02-04

STEDI2

173 enrolled

Brain Neoplasms, Skull Fractures, Intracranial Hemorrhages, Stroke

NCT06057168 2026-01-29

GDX-44-016

Phase 3 Completed

138 enrolled 7 charts

Brain Neoplasms

NCT03262636 2026-01-23

TumorGlow(TM)

363 enrolled

Brain Neoplasms

NCT03873818 2026-01-09

Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain

24 enrolled 13 charts

CNSDermatologic

Brain Neoplasms, Melanoma

NCT07321262 2026-01-08

ML-PNEUMO-BT

1,856 enrolled

Brain Neoplasms

NCT02709226 2025-12-31

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

17 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT06322342 2025-12-26

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

18 enrolled

Neuroinflammatory Diseases, Brain Neoplasms, Glioma, Meningioma, Multiple Sclerosis, Neoplasms, Neurilemmoma, Neurofibroma, Neuroma, Acoustic, Central Nervous System Neoplasms

NCT05465343 2025-12-19

Furmonertinib in EGFR-Mutant NSCLC With Brain Metastases (iFORCE)

24 enrolled

Brain Neoplasms

NCT03638167 2025-12-17

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

11 enrolled