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Phase

Phase 1 1

Status

Withdrawn 1

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NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 6Other hematologic neoplasm 5Sarcoma 2Plasma cell 2Dermatologic 2Myeloid 1Classical hematology 1CNS 1

Conditions

Glioblastoma 23Brain Neoplasms 16Central Nervous System Neoplasms 13Glioma 9Gliosarcoma 8Neuroblastoma 7Astrocytoma 7Neoplasms 6Recurrence 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Melanoma 3Lymphoma 3Lung Neoplasms 3Testicular Neoplasms 2Sarcoma 2Ovarian Neoplasms 2Oligodendroglioma 2Neoplasm Metastasis 2Meningeal Carcinomatosis 2Lymphoma, Non-Hodgkin 2Leukemia, Myeloid, Acute 2Head and Neck Neoplasms 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Waldenstrom Macroglobulinemia 1Vulvar Neoplasms 1Vaginal Neoplasms 1Uterine Neoplasms 1Uterine Cervical Neoplasms 1

Interventions

Radiotherapy 6Psychiatric Rehabilitation 6Filgrastim 6Methylprednisolone 5Melphalan 5Flow Cytometry 5Cyclophosphamide 5Therapeutics 4sargramostim 3Topotecan 3Thiotepa 3Polymerase Chain Reaction 3Early Intervention, Educational 3Dexamethasone 3Caspofungin 3Carboplatin 3Calcium Dobesilate 3Busulfan 3Antilymphocyte Serum 3liposomal amphotericin B 2Vorinostat 2Voriconazole 2Rituximab 2Peripheral Blood Stem Cell Transplantation 2Ondansetron 2Itraconazole 2Immunologic Techniques 2Fentanyl 2Carmustine 2Aprepitant 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Burkitt Lymphoma × Drug Therapy × CNS × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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