Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Dermatologic 11CNS 2

Conditions

Medulloblastoma 6Recurrence 3Glioma 2Glioblastoma 2Carcinoma, Basal Cell 2Astrocytoma 2Stomach Neoplasms 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Pyloric Stenosis, Hypertrophic 1Pinealoma 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Neoplasms, Neuroepithelial 1Neoplasms, Germ Cell and Embryonal 1Neoplasms 1Microphthalmia, Isolated, with Coloboma 5 1Meningioma 1Lymphoma, Follicular 1Hepatoblastoma 1Ependymoma 1Colorectal Neoplasms 1Choroid Plexus Carcinoma 1Central Nervous System Neoplasms 1Breast Neoplasms 1Brain Neoplasms 1

Interventions

sonidegib 2Specimen Handling 1SUB1 protein, human 1Nivolumab 1NVP-LEQ506 1Magnetic Resonance Spectroscopy 1Ipilimumab 1CTLA-4 Antigen 1Antineoplastic Protocols 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Carcinoma, Basal Cell × sonidegib × CNS × Clear all
NCT00880308 2020-12-19

Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors

Novartis

Phase 1 Completed
103 enrolled
CNSDermatologic

Carcinoma, Basal Cell, Medulloblastoma

NCT01208831 2020-12-19

An East Asian Study of LDE225

Novartis

Phase 1 Completed
45 enrolled
CNSDermatologic

Carcinoma, Basal Cell, Medulloblastoma

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