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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Genitourinary 13Thoracic 6Gastrointestinal 5Breast 5Head & Neck 4Dermatologic 4Gynecologic 3Sarcoma 1Other solid neoplasm 1Endocrine 1CNS 1

Conditions

Glioblastoma 5von Hippel-Lindau Disease 1Uterine Cervical Neoplasms 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Salivary Gland Neoplasms 1Pheochromocytoma 1Paraganglioma 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neuroblastoma 1Lung Neoplasms 1Hereditary leiomyomatosis and renal cell cancer 1Head and Neck Neoplasms 1Gliosarcoma 1Glioma 1Endometrial Neoplasms 1Diffuse Intrinsic Pontine Glioma 1Carcinoma, Renal Cell 1Breast Neoplasms 1Brain Neoplasms 1Anus Neoplasms 1

Interventions

pembrolizumab 6Radiosurgery 6Nivolumab 6Magnetic Resonance Spectroscopy 6Ifosfamide 5Bevacizumab 5cabozantinib 4Sunitinib 4Sirolimus 4Granulocyte Colony-Stimulating Factor 4Etoposide 4Carboplatin 4Specimen Handling 3Sorafenib 3Paclitaxel 3Melphalan 3Ipilimumab 3Cyclophosphamide 3Busulfan 3temsirolimus 2lenvatinib 2etoposide phosphate 2cediranib 2belzutifan 2alectinib 2Trastuzumab 2Thiotepa 2Stem Cell Transplantation 2Radiotherapy 2Oxaliplatin 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Carcinoma, Renal Cell × spartalizumab × CNS × Clear all
NCT04895748 2026-03-03

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

Novartis

Phase 1 Terminated
40 enrolled
CNSEndocrineGenitourinary

Hereditary leiomyomatosis and renal cell cancer, Carcinoma, Renal Cell, von Hippel-Lindau Disease, Paraganglioma, Pheochromocytoma

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