Announcements Trials
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Phase

Phase 3 2Phase 2 1

Status

Completed 2Withdrawn 1

Sponsor Class

OTHER 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 2

Conditions

Neuroblastoma 44Ganglioneuroblastoma 5Medulloblastoma 4Glioblastoma 4Brain Neoplasms 4Gliosarcoma 3Glioma 3Central Nervous System Neoplasms 3Astrocytoma 3Rhabdoid Tumor 2Recurrence 2Pinealoma 2Oligodendroglioma 2Pyloric Stenosis, Hypertrophic 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neuroendocrine Tumors 1Neuroectodermal Tumors, Primitive 1Neoplasms 1Neoplasm, Residual 1Lymphoma, Large B-Cell, Diffuse 1Leukemia, Myelomonocytic, Juvenile 1Ependymoma 1Dendritic Cell Sarcoma, Interdigitating 1Burkitt Lymphoma 1

Interventions

Radiotherapy 122Temozolomide 110Carboplatin 53Filgrastim 46Vincristine 43Etoposide 39Cyclophosphamide 37Chemotherapy, Adjuvant 37Cisplatin 36Carmustine 32Irinotecan 27Peripheral Blood Stem Cell Transplantation 25Magnetic Resonance Spectroscopy 24Lomustine 22Thiotepa 21Methotrexate 20Granulocyte Colony-Stimulating Factor 18Procarbazine 16Bevacizumab 16Surgical Procedures, Operative 15O(6)-benzylguanine 14etoposide phosphate 13Drug Therapy 13Topotecan 12Paclitaxel 12Ifosfamide 12Thalidomide 11Radiation 11sargramostim 10Specimen Handling 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Central Nervous System Neoplasms × Isotretinoin × CNS × Clear all
NCT00112502 2021-10-18

Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme

M.D. Anderson Cancer Center

Phase 2 Completed
178 enrolled 23 charts
CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00078988 2015-05-07

High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas

Children's Oncology Group

Phase 3 Completed
1 enrolled
CNS

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms

NCT00003564 2012-02-22

Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas

M.D. Anderson Cancer Center

Phase 3 Withdrawn
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

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