Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Neuroblastoma 17Glioblastoma 11Melanoma 5Brain Neoplasms 5Rhabdoid Tumor 4Osteosarcoma 4Lymphoma 4Glioma 4Sarcoma, Ewing 3Rhabdomyosarcoma 3Recurrence 3Ovarian Neoplasms 3Neoplasm Metastasis 3Leukemia, Myeloid, Acute 3Carcinoma, Hepatocellular 3Breast Neoplasms 3Wilms Tumor 2Prostatic Neoplasms 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pinealoma 2Neurofibromatosis 1 2Neuroectodermal Tumors, Primitive 2Neoplasms, Germ Cell and Embryonal 2Multiple Myeloma 2Meningioma 2Medulloblastoma 2Lymphoma, Non-Hodgkin 2Liver Neoplasms 2Leukemia, Myelomonocytic, Juvenile 2Hepatoblastoma 2

Interventions

Radiotherapy 122Temozolomide 110Carboplatin 53Filgrastim 46Vincristine 43Etoposide 39Cyclophosphamide 37Chemotherapy, Adjuvant 37Cisplatin 36Carmustine 32Irinotecan 27Peripheral Blood Stem Cell Transplantation 25Magnetic Resonance Spectroscopy 24Lomustine 22Thiotepa 21Methotrexate 20Granulocyte Colony-Stimulating Factor 18Procarbazine 16Bevacizumab 16Surgical Procedures, Operative 15O(6)-benzylguanine 14etoposide phosphate 13Drug Therapy 13Topotecan 12Paclitaxel 12Ifosfamide 12Thalidomide 11Radiation 11sargramostim 10Specimen Handling 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Central Nervous System Neoplasms × fludarabine × CNS × Clear all
NCT07390539 2026-02-05

B7-H3.CD28Z.CART in CNS Neoplasms

Dana-Farber Cancer Institute

Phase 1 Not yet recruiting
70 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningeal Neoplasms, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT04792489 2025-04-24

DALY II USA/ MB-CART2019.1 for DLBCL

Miltenyi Biomedicine GmbH

Phase 2 Recruiting
248 enrolled
CNSLymphoid

Lymphoma, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Lymphoma, Mantle-Cell

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