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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Neuroblastoma 22Central Nervous System Neoplasms 9Sarcoma 7Lymphoma 7Wilms Tumor 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neuroectodermal Tumors, Primitive, Peripheral 5Medulloblastoma 5Astrocytoma 5Rhabdomyosarcoma 4Retinoblastoma 4Recurrence 4Leukemia 4Dendritic Cell Sarcoma, Interdigitating 4Brain Neoplasms 4Testicular Neoplasms 3Sarcoma, Ewing 3Rhabdoid Tumor 3Optic Nerve Glioma 3Hepatoblastoma 3Ganglioneuroblastoma 3Familial ependymoma 3Carcinoma, Renal Cell 3Burkitt Lymphoma 3Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Myelodysplastic Syndromes 2Meningeal Carcinomatosis 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2

Interventions

Temozolomide 13Carboplatin 11Filgrastim 9Cyclophosphamide 8Vincristine 7Peripheral Blood Stem Cell Transplantation 7Etoposide 7Cisplatin 7Radiotherapy 5Methotrexate 5Magnetic Resonance Spectroscopy 4Thiotepa 3O(6)-benzylguanine 3Irinotecan 3Granulocyte Colony-Stimulating Factor 3Donepezil 3etoposide phosphate 2Vorinostat 2Topotecan 2Psychiatric Rehabilitation 2Paclitaxel 2Leucovorin 2Gadolinium DTPA 2Erlotinib Hydrochloride 2Cyproheptadine 2Carmustine 2Bortezomib 2Amplified Fragment Length Polymorphism Analysis 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Choroid Plexus Neoplasms × Busulfan × CNS × Clear all
NCT00006246 2009-10-07

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Pediatric Brain Tumor Consortium

Phase 1 Completed
28 enrolled
CNSLymphoidOther hematologic neoplasmOther solid neoplasmSarcoma

Familial ependymoma, Astrocytoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Recurrence, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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