Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Glioblastoma 17Gliosarcoma 15Central Nervous System Neoplasms 14Astrocytoma 13Brain Neoplasms 10Glioma 8Oligodendroglioma 7Optic Nerve Glioma 3Medulloblastoma 3Familial ependymoma 3Choroid Plexus Neoplasms 3Ependymoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Sarcoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Lymphoma 1

Interventions

Temozolomide 13Carboplatin 11Filgrastim 9Cyclophosphamide 8Vincristine 7Peripheral Blood Stem Cell Transplantation 7Etoposide 7Cisplatin 7Radiotherapy 5Methotrexate 5Magnetic Resonance Spectroscopy 4Thiotepa 3O(6)-benzylguanine 3Irinotecan 3Granulocyte Colony-Stimulating Factor 3Donepezil 3etoposide phosphate 2Vorinostat 2Topotecan 2Psychiatric Rehabilitation 2Paclitaxel 2Leucovorin 2Gadolinium DTPA 2Erlotinib Hydrochloride 2Cyproheptadine 2Carmustine 2Bortezomib 2Amplified Fragment Length Polymorphism Analysis 22-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 22,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Choroid Plexus Neoplasms × O(6)-benzylguanine × CNS × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

National Cancer Institute (NCI)

Phase 1 Completed
72 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00003765 2013-02-05

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
36 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

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