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Phase

Phase 1 1

Status

Withdrawn 1

Sponsor Class

NETWORK 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 2Other hematologic neoplasm 2Lymphoid 2Plasma cell 1Myeloid 1Dermatologic 1Classical hematology 1CNS 1

Conditions

Glioblastoma 23Brain Neoplasms 16Central Nervous System Neoplasms 13Glioma 9Gliosarcoma 8Neuroblastoma 7Astrocytoma 7Neoplasms 6Recurrence 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Melanoma 3Lymphoma 3Lung Neoplasms 3Testicular Neoplasms 2Sarcoma 2Ovarian Neoplasms 2Oligodendroglioma 2Neoplasm Metastasis 2Meningeal Carcinomatosis 2Lymphoma, Non-Hodgkin 2Leukemia, Myeloid, Acute 2Head and Neck Neoplasms 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Waldenstrom Macroglobulinemia 1Vulvar Neoplasms 1Vaginal Neoplasms 1Uterine Neoplasms 1Uterine Cervical Neoplasms 1

Interventions

Radiotherapy 5Melphalan 4Filgrastim 4Busulfan 4Topotecan 3Methylprednisolone 3Cyclophosphamide 3Carboplatin 3Vorinostat 2Voriconazole 2Thiotepa 2Therapeutics 2Psychiatric Rehabilitation 2Polymerase Chain Reaction 2Itraconazole 2Flow Cytometry 2Early Intervention, Educational 2Antilymphocyte Serum 2Amplified Fragment Length Polymorphism Analysis 2trioctyl phosphine oxide 1sargramostim 1liposomal amphotericin B 1ispinesib 1imetelstat 1gallium nitrate 1fludarabine phosphate 1exatecan 1etoposide phosphate 1becatecarin 1alvocidib 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Dendritic Cell Sarcoma, Interdigitating × Drug Therapy × CNS × Clear all
NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Children's Oncology Group

Phase 1 Withdrawn
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

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