Announcements Trials
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Phase

Phase 3 2Phase 1 2Phase 2 1

Status

Completed 3Recruiting 2

Sponsor Class

NETWORK 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5

Conditions

Central Nervous System Neoplasms 36Neuroblastoma 35Brain Neoplasms 25Medulloblastoma 22Astrocytoma 10Glioma 8Glioblastoma 7Choroid Plexus Neoplasms 7Rhabdoid Tumor 6Oligodendroglioma 6Neuroectodermal Tumors, Primitive 6Ependymoma 6Breast Neoplasms 6Sarcoma 5Ovarian Neoplasms 5Neoplasms 5Ganglioneuroblastoma 5Esthesioneuroblastoma, Olfactory 5Carcinoma, Non-Small-Cell Lung 5Testicular Neoplasms 4Testicular Germ Cell Tumor 4Small Cell Lung Carcinoma 4Lung Neoplasms 4Head and Neck Neoplasms 4Gliosarcoma 4Thyroid Neoplasms 3Teratoma 3Squamous Cell Carcinoma of Head and Neck 3Seminoma 3Endodermal Sinus Tumor 3

Interventions

Cyclophosphamide 8dinutuximab 7Magnetic Resonance Spectroscopy 7Topotecan 6Doxorubicin 6sargramostim 5Vincristine 5Stem Cell Transplantation 5Radiation 5Platinum 5Melphalan 5Isotretinoin 5Colony-Stimulating Factors 5Cisplatin 5Biopsy 51,2-diaminocyclohexaneplatinum II citrate 5Temozolomide 4Specimen Handling 4Irinotecan 4Etoposide 4Congresses as Topic 4Carboplatin 4Thiotepa 3Busulfan 33-Iodobenzylguanidine 3etoposide phosphate 2Razoxane 2Dexrazoxane 2temsirolimus 1lorlatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Ganglioneuroblastoma × Cisplatin × CNS × Clear all
NCT06172296 2026-06-03

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 3 Recruiting
478 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03786783 2026-06-02

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 2 Completed
42 enrolled 12 charts
CNS

Ganglioneuroblastoma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Children's Oncology Group

Phase 1 Completed
99 enrolled 11 charts
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT01798004 2024-07-15

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Children's Oncology Group

Phase 1 Completed
150 enrolled 9 charts
CNS

Neuroblastoma, Ganglioneuroblastoma

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