Announcements Trials
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Phase

Phase 3 2Phase 1 2Phase 2 1

Status

Completed 3Recruiting 2

Sponsor Class

NETWORK 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5

Conditions

Neuroblastoma 44Medulloblastoma 9Lymphoma 9Sarcoma 8Brain Neoplasms 8Neuroectodermal Tumors, Primitive, Peripheral 7Central Nervous System Neoplasms 7Rhabdomyosarcoma 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Wilms Tumor 5Sarcoma, Ewing 5Leukemia 5Ganglioneuroblastoma 5Burkitt Lymphoma 5Astrocytoma 5Rhabdoid Tumor 4Lymphoma, Non-Hodgkin 4Lymphoma, Mantle-Cell 4Lymphoma, Large-Cell, Immunoblastic 4Lymphoma, Large B-Cell, Diffuse 4Lymphoma, Follicular 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Myeloid, Acute 4Leukemia, Lymphocytic, Chronic, B-Cell 4Hepatoblastoma 4Glioma 4Dendritic Cell Sarcoma, Interdigitating 4Testicular Neoplasms 3Retinoblastoma 3Recurrence 3

Interventions

Cyclophosphamide 8dinutuximab 7Magnetic Resonance Spectroscopy 7Topotecan 6Doxorubicin 6sargramostim 5Vincristine 5Stem Cell Transplantation 5Radiation 5Platinum 5Melphalan 5Isotretinoin 5Colony-Stimulating Factors 5Cisplatin 5Biopsy 51,2-diaminocyclohexaneplatinum II citrate 5Temozolomide 4Specimen Handling 4Irinotecan 4Etoposide 4Congresses as Topic 4Carboplatin 4Thiotepa 3Busulfan 33-Iodobenzylguanidine 3etoposide phosphate 2Razoxane 2Dexrazoxane 2temsirolimus 1lorlatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Ganglioneuroblastoma × Melphalan × CNS × Clear all
NCT06172296 2026-06-03

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 3 Recruiting
478 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03786783 2026-06-02

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 2 Completed
42 enrolled 12 charts
CNS

Ganglioneuroblastoma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Children's Oncology Group

Phase 1 Completed
99 enrolled 11 charts
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT01798004 2024-07-15

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Children's Oncology Group

Phase 1 Completed
150 enrolled 9 charts
CNS

Neuroblastoma, Ganglioneuroblastoma

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