Announcements Trials
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Phase

Phase 3 2Phase 2 1

Status

Recruiting 2Completed 1

Sponsor Class

NIH 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Central Nervous System Neoplasms 21Neuroblastoma 18Medulloblastoma 14Brain Neoplasms 13Astrocytoma 10Sarcoma 6Rhabdoid Tumor 6Retinoblastoma 6Ependymoma 6Oligodendroglioma 5Glioma 5Testicular Neoplasms 4Neuroectodermal Tumors, Primitive, Peripheral 4Lymphoma 4Wilms Tumor 3Teratoma 3Rhabdomyosarcoma 3Recurrence 3Pinealoma 3Ovarian Neoplasms 3Neuroectodermal Tumors, Primitive 3Liver Neoplasms 3Kidney Neoplasms 3Hepatoblastoma 3Gliosarcoma 3Glioblastoma 3Ganglioneuroblastoma 3Familial ependymoma 3Desmoplastic Small Round Cell Tumor 3Choroid Plexus Neoplasms 3

Interventions

Cyclophosphamide 8dinutuximab 7Magnetic Resonance Spectroscopy 7Topotecan 6Doxorubicin 6sargramostim 5Vincristine 5Stem Cell Transplantation 5Radiation 5Platinum 5Melphalan 5Isotretinoin 5Colony-Stimulating Factors 5Cisplatin 5Biopsy 51,2-diaminocyclohexaneplatinum II citrate 5Temozolomide 4Specimen Handling 4Irinotecan 4Etoposide 4Congresses as Topic 4Carboplatin 4Thiotepa 3Busulfan 33-Iodobenzylguanidine 3etoposide phosphate 2Razoxane 2Dexrazoxane 2temsirolimus 1lorlatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Ganglioneuroblastoma × Thiotepa × CNS × Clear all
NCT06172296 2026-06-03

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 3 Recruiting
478 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03786783 2026-06-02

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 2 Completed
42 enrolled 12 charts
CNS

Ganglioneuroblastoma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

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