Announcements Trials
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Phase

Phase 3 1Phase 1 1

Status

Recruiting 1Completed 1

Sponsor Class

NETWORK 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Neuroblastoma 16Central Nervous System Neoplasms 13Brain Neoplasms 9Medulloblastoma 8Rhabdoid Tumor 6Astrocytoma 6Sarcoma 5Glioma 5Oligodendroglioma 4Lymphoma 4Pinealoma 3Osteosarcoma 3Optic Nerve Glioma 3Ependymoma 3Testicular Neoplasms 2Testicular Germ Cell Tumor 2Teratoma 2Spinal Cord Neoplasms 2Rhabdomyosarcoma 2Recurrence 2Ovarian Neoplasms 2Neuroectodermal Tumors, Primitive, Peripheral 2Neoplasms, Germ Cell and Embryonal 2Neoplasms 2Kidney Neoplasms 2Glioblastoma 2Ganglioneuroblastoma 2Familial ependymoma 2Drug-Related Side Effects and Adverse Reactions 2Choroid Plexus Neoplasms 2

Interventions

Cyclophosphamide 8dinutuximab 7Magnetic Resonance Spectroscopy 7Topotecan 6Doxorubicin 6sargramostim 5Vincristine 5Stem Cell Transplantation 5Radiation 5Platinum 5Melphalan 5Isotretinoin 5Colony-Stimulating Factors 5Cisplatin 5Biopsy 51,2-diaminocyclohexaneplatinum II citrate 5Temozolomide 4Specimen Handling 4Irinotecan 4Etoposide 4Congresses as Topic 4Carboplatin 4Thiotepa 3Busulfan 33-Iodobenzylguanidine 3etoposide phosphate 2Razoxane 2Dexrazoxane 2temsirolimus 1lorlatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Ganglioneuroblastoma × etoposide phosphate × CNS × Clear all
NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Children's Oncology Group

Phase 1 Completed
99 enrolled 11 charts
CNS

Neuroblastoma, Ganglioneuroblastoma

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