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Phase

Phase 3 5Phase 2 4Phase 1 3Phase NA 2Phase 1/2 2Phase EARLY_PHASE1 1

Status

Recruiting 4Active not recruiting 1

Sponsor Class

OTHER 2NETWORK 2NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5

Conditions

Brain Neoplasms 133Glioblastoma 92Astrocytoma 44Neuroblastoma 40Glioma 40Central Nervous System Neoplasms 38Neoplasms 26Breast Neoplasms 25Neoplasm Metastasis 24Oligodendroglioma 20Gliosarcoma 19Carcinoma, Non-Small-Cell Lung 18Lymphoma, Follicular 14Recurrence 13Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Medulloblastoma 13Burkitt Lymphoma 13Testicular Neoplasms 12Lymphoma, T-Cell, Cutaneous 12Lymphoma, Non-Hodgkin 12Lymphoma, Mantle-Cell 12Lymphoma, Large-Cell, Immunoblastic 12Lymphoma, Large B-Cell, Diffuse 12Lymphoma, B-Cell, Marginal Zone 12Leukemia, Lymphocytic, Chronic, B-Cell 12Hodgkin Disease 12Sezary Syndrome 11Primary Myelofibrosis 11Mycosis Fungoides 11Leukemia, Myeloid, Chronic-Phase 11

Interventions

dinutuximab 3Magnetic Resonance Spectroscopy 3Doxorubicin 3Cyclophosphamide 3Carboplatin 3Biopsy 3Vincristine 2Topotecan 2Thiotepa 2Temozolomide 2Stem Cell Transplantation 2Specimen Handling 2Radiation 2Platinum 2Melphalan 2Isotretinoin 2Irinotecan 2Etoposide 2Cisplatin 21,2-diaminocyclohexaneplatinum II citrate 2sargramostim 1lorlatinib 1etoposide phosphate 1Watchful Waiting 1Transurethral Resection of Bladder 1Razoxane 1Radiotherapy 1Observation 1Nuclear Medicine Department, Hospital 1Leukapheresis 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 3 × Ganglioneuroblastoma × CNS × Clear all
NCT06172296 2026-06-03

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 3 Recruiting
478 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT02176967 2026-05-05

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Children's Oncology Group

Phase 3 Active not recruiting
621 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT07375563 2026-01-29

NB-NK-2026

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Phase 3 Recruiting
5 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT06071897 2023-10-10

Induction Chemoimmunotherapy for Patients With High-risk Neuroblastoma

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Phase 3 Recruiting
15 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

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