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Phase

Phase 2 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Myeloid 1Lymphoid 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Wilms Tumor 2Sarcoma, Ewing 2Sarcoma 2Rhabdomyosarcoma 2Rhabdoid Tumor 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Medulloblastoma 2Lymphoma, Non-Hodgkin 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Glioma 2Ependymoma 2Central Nervous System Neoplasms 2Xanthogranuloma, Juvenile 1Hodgkin Disease 1Histiocytic Sarcoma 1

Interventions

Flow Cytometry 5Therapeutics 4Psychiatric Rehabilitation 4Cyclophosphamide 4Radiotherapy 3Polymerase Chain Reaction 3Melphalan 3Amplified Fragment Length Polymorphism Analysis 3sargramostim 2liposomal amphotericin B 2Thiotepa 2Peripheral Blood Stem Cell Transplantation 2Ondansetron 2Methylprednisolone 2Itraconazole 2Ipilimumab 2Immunologic Techniques 2Filgrastim 2Fentanyl 2Early Intervention, Educational 2Dexamethasone 2Caspofungin 2Calcium Dobesilate 2CTLA-4 Antigen 2Aprepitant 2Alemtuzumab 2thymoglobulin 1tazemetostat 1imetelstat 1dostarlimab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Hodgkin Disease × tazemetostat × CNS × Clear all
NCT03213665 2026-04-13

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

National Cancer Institute (NCI)

Phase 2 Completed
20 enrolled 12 charts
CNSGastrointestinalGenitourinaryLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Hodgkin Disease, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

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