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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Glioblastoma 202Central Nervous System Neoplasms 122Brain Neoplasms 107Gliosarcoma 85Glioma 68Astrocytoma 63Oligodendroglioma 34Neuroblastoma 29Medulloblastoma 20Neoplasm Metastasis 19Carcinoma, Non-Small-Cell Lung 15Lung Neoplasms 14Ependymoma 11Diffuse Intrinsic Pontine Glioma 11Breast Neoplasms 11Meningeal Carcinomatosis 8Neoplasms 7Lymphoma 7Squamous Cell Carcinoma of Head and Neck 6Sarcoma 6Optic Nerve Glioma 6Neuroectodermal Tumors, Primitive 6Lymphoma, Follicular 6Head and Neck Neoplasms 6Esthesioneuroblastoma, Olfactory 6Burkitt Lymphoma 6Spinal Cord Neoplasms 5Salivary Gland Neoplasms 5Rhabdoid Tumor 5Recurrence 5

Interventions

Radiotherapy 1Lovastatin 1AZD1390 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Inhibition, Psychological × Radiotherapy × CNS × Clear all
NCT03423628 2025-12-22

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

AstraZeneca

Phase 1 Recruiting
180 enrolled
CNS

Brain Neoplasms, Glioblastoma, Inhibition, Psychological, Meningeal Neoplasms, Hereditary Sensory and Autonomic Neuropathies

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