Announcements Trials
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Phase

Phase 1 2Phase NA 1Phase EARLY_PHASE1 1Phase 2 1

Status

Completed 3Withdrawn 1Terminated 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Lymphoid 160Other hematologic neoplasm 65Myeloid 14Sarcoma 13Plasma cell 11Classical hematology 7CNS 5Dermatologic 4Other neoplasm 1

Conditions

Lymphoma 5Central Nervous System Neoplasms 4Neuroblastoma 2Meningeal Carcinomatosis 2Brain Neoplasms 2Vasculitis, Central Nervous System 1Thrombocytopenia 1Stiff-Person Syndrome 1Rhabdoid Tumor 1Recurrence 1Rasmussen subacute encephalitis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polyradiculoneuropathy, Chronic Inflammatory Demyelinating 1Opsoclonus-Myoclonus Syndrome 1Neurotoxicity Syndromes 1Neuromyelitis Optica 1Neurofibromatosis 1 1Myasthenia Gravis 1Medulloblastoma 1Lymphoma, Non-Hodgkin 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myeloid, Acute 1Leukemia 1Lambert-Eaton Myasthenic Syndrome 1Intraocular Lymphoma 1HIV Infections 1Ependymoma 1Drug-Related Side Effects and Adverse Reactions 1Breast Neoplasms 1Autoimmune Diseases of the Nervous System 1

Interventions

Filgrastim 11Temozolomide 9Melphalan 9Cyclophosphamide 9Radiotherapy 7Busulfan 7Magnetic Resonance Spectroscopy 6Rituximab 5Psychiatric Rehabilitation 5Methotrexate 5Etoposide 5Cytarabine 5Carboplatin 5sargramostim 4fludarabine 4etoposide phosphate 4Thiotepa 4Nivolumab 4Methylprednisolone 4Flow Cytometry 4Alemtuzumab 4Vincristine 3Topotecan 3Specimen Handling 3Peripheral Blood Stem Cell Transplantation 3Pemetrexed 3Granulocyte Colony-Stimulating Factor 3Early Intervention, Educational 3Drug Therapy 3Dexamethasone 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Lymphoma × Cytarabine × CNS × Clear all
NCT03654716 2025-02-14

Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer

Dana-Farber Cancer Institute

Phase 1 Completed
21 enrolled
CNSLymphoidOther hematologic neoplasm

Brain Neoplasms, Leukemia, Lymphoma

NCT00074165 2023-07-06

Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen

OHSU Knight Cancer Institute

Phase 2 Terminated
17 enrolled 7 charts
CNSClassical hematologyLymphoid

Lymphoma, Thrombocytopenia, Central Nervous System Neoplasms, Intraocular Lymphoma, Drug-Related Side Effects and Adverse Reactions

NCT02130869 2017-12-22

A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

St. Jude Children's Research Hospital

Phase 1 Completed
8 enrolled
CNSLymphoid

Lymphoma, Neuroblastoma

NCT00416819 2015-08-20

Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

University of California, San Francisco

Phase NA Completed
10 enrolled
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT00734773 2012-05-18

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Northwestern University

Phase EARLY_PHASE1 Withdrawn
CNSLymphoid

Lymphoma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

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