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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 52Other hematologic neoplasm 22Lymphoid 20Dermatologic 5Thoracic 2Sarcoma 2Other neoplasm 1Genitourinary 1Gastrointestinal 1CNS 1

Conditions

Brain Neoplasms 2310Glioblastoma 2014Glioma 1399Central Nervous System Neoplasms 692Astrocytoma 667Neuroblastoma 647Gliosarcoma 480Neoplasms 405Oligodendroglioma 404Breast Neoplasms 327Medulloblastoma 307Carcinoma, Non-Small-Cell Lung 255Meningioma 229Recurrence 224Sarcoma 214Melanoma 206Neoplasm Metastasis 202Lung Neoplasms 199Ependymoma 199Neurofibromatosis 1 169Lymphoma 161Meningeal Carcinomatosis 138Osteosarcoma 134Ovarian Neoplasms 132Wilms Tumor 123Precursor Cell Lymphoblastic Leukemia-Lymphoma 123Head and Neck Neoplasms 117Lymphoma, Non-Hodgkin 116Diffuse Intrinsic Pontine Glioma 113Rhabdomyosarcoma 106

Interventions

ripretinib 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Mastocytosis, Systemic × CNS × Clear all
NCT02571036 2023-12-13

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

Deciphera Pharmaceuticals, LLC

Phase 1 Completed
282 enrolled
CNSDermatologicGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

Mast Cell Activation Disorders, Carcinoma, Non-Small-Cell Lung, Glioma, Leukemia, Mast-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Penile Neoplasms, Sarcoma, Mastocytosis, Systemic, Gastrointestinal Stromal Tumors, Renal Insufficiency

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