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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Dermatologic 3Genitourinary 2Thoracic 1Sarcoma 1Lymphoid 1Gastrointestinal 1CNS 1Breast 1

Conditions

Neuroblastoma 22Central Nervous System Neoplasms 9Sarcoma 7Lymphoma 7Wilms Tumor 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neuroectodermal Tumors, Primitive, Peripheral 5Medulloblastoma 5Astrocytoma 5Rhabdomyosarcoma 4Retinoblastoma 4Recurrence 4Leukemia 4Dendritic Cell Sarcoma, Interdigitating 4Brain Neoplasms 4Testicular Neoplasms 3Sarcoma, Ewing 3Rhabdoid Tumor 3Optic Nerve Glioma 3Hepatoblastoma 3Ganglioneuroblastoma 3Familial ependymoma 3Carcinoma, Renal Cell 3Burkitt Lymphoma 3Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Myelodysplastic Syndromes 2Meningeal Carcinomatosis 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2

Interventions

Radiosurgery 22Nivolumab 21Ipilimumab 19pembrolizumab 15Temozolomide 11dabrafenib 10binimetinib 10encorafenib 8Cyclophosphamide 8trametinib 7Magnetic Resonance Spectroscopy 7Bevacizumab 6fludarabine 5cobimetinib 5Specimen Handling 5CTLA-4 Antigen 5fludarabine phosphate 3aldesleukin 3Vemurafenib 3Thalidomide 3Paclitaxel 3Oxaliplatin 3Interleukin-2 3Gemcitabine 3Drug Therapy 3Carboplatin 3130-nm albumin-bound paclitaxel 3ulixertinib 2tovorafenib 2relatlimab 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Melanoma × Busulfan × CNS × Clear all
NCT01625351 2026-02-06

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

St. Jude Children's Research Hospital

Phase 1 Completed
23 enrolled
CNSDermatologicGastrointestinalGenitourinaryLymphoidSarcoma

Carcinoma, Renal Cell, Digestive System Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Adenocarcinoma, Clear Cell, Rhabdoid Tumor

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