Clinical Trials Browser

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT03898908 2025-05-21

EBRAIN-MEL

Phase 2 Completed

48 enrolled 24 charts

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT03184038 2025-05-15

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

Phase NA Recruiting

90 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT05900908 2025-04-10

PATHWAyS

Phase 4 Withdrawn

CNS

Glioblastoma, Neoplasm Metastasis, Neoplasms, Recurrence

NCT04895592 2025-03-21

Radiosurgery Before Surgery for the Treatment of Brain Metastases

Phase EARLY_PHASE1 Active not recruiting

26 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT02953717 2023-09-13

Cognitive Outcome After SRS or WBRT in Patients With Multiple Brain Metastases (CAR-Study B)

Phase NA Unknown

81 enrolled

CNS

Anxiety Disorders, Brain Neoplasms, Depression, Fatigue, Neoplasm Metastasis

NCT00003308 2023-06-22

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

Phase 2 Completed

CNSDermatologicGenitourinaryGynecologicSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Chondrosarcoma, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00377156 2022-09-16

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Completed

213 enrolled 16 charts

BreastCNSGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Breast Neoplasms, Male

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Phase 3 Completed

194 enrolled 11 charts

CNS

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT02355613 2022-05-04

Comparative Evaluation of Two Different Radiosurgery

Phase NA Completed

250 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT02567643 2022-01-11

Stereotactic Radiosurgery (SRS) for Multiple CNS Mets

Phase NA Withdrawn

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT02953756 2020-08-14

Cognitive Outcome After Gamma Knife Radiosurgery in Patients With Brain Metastases (CAR-Study A)

Completed

92 enrolled

CNS

Anxiety Disorders, Brain Neoplasms, Depression, Fatigue, Neoplasm Metastasis

NCT00003320 2020-08-03

Radiation Therapy Following Surgery to Remove Brain Metastases

Phase NA Completed

20 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00006259 2020-07-27

Stereotactic Radiation Therapy in Treating Patients With Brain Metastases

Phase 2 Completed

10 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00837928 2018-05-17

Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors

Phase 1 Completed

18 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00547131 2018-04-17

Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors

Phase 1 Completed

12 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Central Nervous System Neoplasms

NCT01970644 2016-05-30

Neurocognition After Gamma Knife Radiosurgery for Multiple Brian Metastases

Terminated

3 enrolled

CNS

Brain Neoplasms, Cognition Disorders, Neoplasm Metastasis

NCT01169129 2014-02-04

Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases

Phase 3 Withdrawn

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00811655 2013-11-25

Stereotactic Radiosurgery in Treating Patients With Brain Metastases

Phase 2 Terminated

6 enrolled 6 charts

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00002708 2013-11-19

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

Phase 3 Completed

333 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00385398 2013-09-02

QOL-Stereotactic RadioSurgery, Temozolomide + Erlotinib-Rx of 1-3 Brain Metastases in NSCLC

Phase 2 Withdrawn

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00003911 2013-01-31

S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases

Phase 2 Terminated

2 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00738335 2012-10-04

Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases

Phase 1 Withdrawn

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00002899 2012-07-02

Adjuvant Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Terminated

340 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT01353573 2011-05-13

TRICK

Phase 3 Unknown

60 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00124761 2010-09-06

A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases

Phase 3 Completed

22 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

Clinical Trials

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases

ADORATION

Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

EBRAIN-MEL

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

PATHWAyS

Radiosurgery Before Surgery for the Treatment of Brain Metastases

Cognitive Outcome After SRS or WBRT in Patients With Multiple Brain Metastases (CAR-Study B)

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Comparative Evaluation of Two Different Radiosurgery

Stereotactic Radiosurgery (SRS) for Multiple CNS Mets

Cognitive Outcome After Gamma Knife Radiosurgery in Patients With Brain Metastases (CAR-Study A)

Radiation Therapy Following Surgery to Remove Brain Metastases

Stereotactic Radiation Therapy in Treating Patients With Brain Metastases

Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors

Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors

Neurocognition After Gamma Knife Radiosurgery for Multiple Brian Metastases

Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases

Stereotactic Radiosurgery in Treating Patients With Brain Metastases

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

QOL-Stereotactic RadioSurgery, Temozolomide + Erlotinib-Rx of 1-3 Brain Metastases in NSCLC

S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases

Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases

Adjuvant Radiation Therapy in Treating Patients With Brain Metastases

TRICK

A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases