Clinical Trials Browser

NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT06500455 2026-05-04

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Phase 3 Recruiting

269 enrolled

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT01592968 2026-03-09

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

Phase 3 Active not recruiting

88 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT04365374 2025-10-07

Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

Phase 3 Active not recruiting

230 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00377156 2022-09-16

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Completed

213 enrolled 16 charts

BreastCNSGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Breast Neoplasms, Male

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Phase 3 Completed

194 enrolled 11 charts

CNS

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT02201381 2022-07-18

METRICS

Phase 3 Withdrawn

BreastCNSGastrointestinalGynecologic

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Triple Negative Breast Neoplasms

NCT00369785 2021-10-20

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Phase 3 Completed

198 enrolled 10 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Fatigue, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Radiation Injuries, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00005887 2021-08-23

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Phase 3 Completed

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00566852 2017-08-21

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Phase 3 Completed

554 enrolled 12 charts

CNS

Brain Neoplasms, Neoplasm Metastasis, Neurotoxicity Syndromes

NCT00280475 2016-09-22

A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis

Phase 3 Completed

270 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00030628 2016-07-07

Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Completed

480 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT01169129 2014-02-04

Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases

Phase 3 Withdrawn

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00002708 2013-11-19

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

Phase 3 Completed

333 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00003563 2013-10-31

Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases

Phase 3 Completed

430 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00403065 2013-08-26

Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery

Phase 3 Completed

1,000 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00083304 2013-05-10

ENRICH

Phase 3 Completed

368 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT00003941 2012-09-24

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer

Phase 3 Completed

222 enrolled

CNSGenitourinary

Teratoma, Testicular, Testicular Germ Cell Tumor, Brain Neoplasms, Mediastinal Neoplasms, Neoplasm Metastasis, Teratoma, Testicular Neoplasms, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor

NCT00020839 2012-09-24