Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 4Genitourinary 4Gastrointestinal 3CNS 3Myeloid 2Lymphoid 2Plasma cell 1Other solid neoplasm 1Other hematologic neoplasm 1Dermatologic 1

Conditions

Neuroblastoma 101Central Nervous System Neoplasms 37Medulloblastoma 35Brain Neoplasms 33Glioblastoma 20Sarcoma 16Rhabdoid Tumor 14Glioma 13Ependymoma 12Astrocytoma 11Osteosarcoma 10Neuroectodermal Tumors, Primitive 10Recurrence 9Neoplasms 9Lymphoma 9Breast Neoplasms 9Sarcoma, Ewing 8Oligodendroglioma 8Melanoma 8Ganglioneuroblastoma 8Choroid Plexus Neoplasms 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Ovarian Neoplasms 7Neoplasm Metastasis 7Lymphoma, Non-Hodgkin 7Leukemia, Myeloid, Acute 7Gliosarcoma 7Rhabdomyosarcoma 6Multiple Myeloma 6Wilms Tumor 5

Interventions

Sirolimus 3Melphalan 3Granulocyte Colony-Stimulating Factor 3Cyclophosphamide 3Automobiles 3pembrolizumab 2fludarabine 2etoposide phosphate 2Stem Cell Transplantation 2Mesna 2Immunotherapy 2Gemcitabine 2Etoposide 2Carboplatin 2Busulfan 2vorasidenib 1trametinib 1tozuleristide 1sonidegib 1sodium thiosulfate 1ripretinib 1ribociclib 1pegylated granulocyte colony-stimulating factor 1lutetium Lu 177 dotatate 1interferon gamma-1b 1fludarabine phosphate 1Watchful Waiting 1Vorinostat 1Ursodeoxycholic Acid 1Topotecan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × Cyclophosphamide × CNS × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT02574728 2026-03-02

AflacST1502

Emory University

Phase 2 Active not recruiting
46 enrolled
CNSMyeloidSarcoma

Brain Neoplasms, Carcinoma, Ependymoma, Histiocytosis, Langerhans-Cell, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT02390843 2020-04-03

AflacST1402

Emory University

Phase 1 Completed
13 enrolled
CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

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