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Phase

Phase 1/2 1

Status

Unknown 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Brain Neoplasms 3Oligodendroglioma 2Medulloblastoma 2Central Nervous System Neoplasms 2Astrocytoma 2Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Germ Cell and Embryonal 1Gliosarcoma 1Glioma 1Glioblastoma 1Familial ependymoma 1Drug-Related Side Effects and Adverse Reactions 1

Interventions

Sirolimus 3Melphalan 3Granulocyte Colony-Stimulating Factor 3Cyclophosphamide 3Automobiles 3pembrolizumab 2fludarabine 2etoposide phosphate 2Stem Cell Transplantation 2Mesna 2Immunotherapy 2Gemcitabine 2Etoposide 2Carboplatin 2Busulfan 2vorasidenib 1trametinib 1tozuleristide 1sonidegib 1sodium thiosulfate 1ripretinib 1ribociclib 1pegylated granulocyte colony-stimulating factor 1lutetium Lu 177 dotatate 1interferon gamma-1b 1fludarabine phosphate 1Watchful Waiting 1Vorinostat 1Ursodeoxycholic Acid 1Topotecan 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × Mannitol × CNS × Clear all
NCT00983398 2021-10-26

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

OHSU Knight Cancer Institute

Phase 1/2 Unknown
17 enrolled
CNS

Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive

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