Announcements Trials
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Phase

Phase 1 2

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Lymphoid 2Genitourinary 2Gastrointestinal 2Dermatologic 2CNS 2Plasma cell 1Other hematologic neoplasm 1Myeloid 1

Conditions

Neuroblastoma 17Glioblastoma 11Melanoma 5Brain Neoplasms 5Rhabdoid Tumor 4Osteosarcoma 4Lymphoma 4Glioma 4Sarcoma, Ewing 3Rhabdomyosarcoma 3Recurrence 3Ovarian Neoplasms 3Neoplasm Metastasis 3Leukemia, Myeloid, Acute 3Carcinoma, Hepatocellular 3Breast Neoplasms 3Wilms Tumor 2Prostatic Neoplasms 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pinealoma 2Neurofibromatosis 1 2Neuroectodermal Tumors, Primitive 2Neoplasms, Germ Cell and Embryonal 2Multiple Myeloma 2Meningioma 2Medulloblastoma 2Lymphoma, Non-Hodgkin 2Liver Neoplasms 2Leukemia, Myelomonocytic, Juvenile 2Hepatoblastoma 2

Interventions

Sirolimus 3Melphalan 3Granulocyte Colony-Stimulating Factor 3Cyclophosphamide 3Automobiles 3pembrolizumab 2fludarabine 2etoposide phosphate 2Stem Cell Transplantation 2Mesna 2Immunotherapy 2Gemcitabine 2Etoposide 2Carboplatin 2Busulfan 2vorasidenib 1trametinib 1tozuleristide 1sonidegib 1sodium thiosulfate 1ripretinib 1ribociclib 1pegylated granulocyte colony-stimulating factor 1lutetium Lu 177 dotatate 1interferon gamma-1b 1fludarabine phosphate 1Watchful Waiting 1Vorinostat 1Ursodeoxycholic Acid 1Topotecan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × fludarabine × CNS × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT01625351 2026-02-06

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

St. Jude Children's Research Hospital

Phase 1 Completed
23 enrolled
CNSDermatologicGastrointestinalGenitourinaryLymphoidSarcoma

Carcinoma, Renal Cell, Digestive System Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Adenocarcinoma, Clear Cell, Rhabdoid Tumor

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