Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Recruiting 2

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 3Thoracic 2Sarcoma 2NET 2Endocrine 2CNS 2Other neoplasm 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Head & Neck 1Genitourinary 1

Conditions

Brain Neoplasms 83Glioma 73Glioblastoma 73Neuroblastoma 27Neoplasms 22Astrocytoma 20Neurofibromatosis 1 19Ependymoma 19Sarcoma 18Medulloblastoma 18Central Nervous System Neoplasms 18Rhabdoid Tumor 15Melanoma 15Meningioma 14Carcinoma, Non-Small-Cell Lung 14Osteosarcoma 13Wilms Tumor 12Sarcoma, Ewing 12Rhabdomyosarcoma 12Breast Neoplasms 12Neurofibroma, Plexiform 11Hepatoblastoma 11Diffuse Intrinsic Pontine Glioma 10Neuroectodermal Tumors, Primitive, Peripheral 9Lymphoma, Non-Hodgkin 9Histiocytosis, Langerhans-Cell 9Thyroid Neoplasms 8Recurrence 8Pancreatic Neoplasms 8Neoplasm Metastasis 8

Interventions

Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neoplasms by Histologic Type × CNS × 30 days × Clear all
NCT07416188 2026-06-05

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
40 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

NCT03911388 2026-05-15

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

M.D. Anderson Cancer Center

Phase 1 Recruiting
24 enrolled
CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

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