Announcements Trials
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Phase

Phase 4 1Phase 1/2 1

Status

Completed 3Recruiting 2

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Myeloid 1

Conditions

Brain Neoplasms 362Glioblastoma 299Glioma 239Neuroblastoma 95Neoplasms 70Central Nervous System Neoplasms 62Astrocytoma 61Meningioma 59Breast Neoplasms 51Lung Neoplasms 46Carcinoma, Non-Small-Cell Lung 46Melanoma 40Sarcoma 35Medulloblastoma 33Meningeal Carcinomatosis 32Recurrence 31Neoplasm Metastasis 28Diffuse Intrinsic Pontine Glioma 28Prostatic Neoplasms 27Pheochromocytoma 26Paraganglioma 26Neurofibromatosis 1 26Pancreatic Neoplasms 24Ovarian Neoplasms 24Oligodendroglioma 22Ependymoma 21Osteosarcoma 20Head and Neck Neoplasms 20Spinal Cord Neoplasms 19Kidney Neoplasms 19

Interventions

trametinib 1mirdametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Recruiting × Neurocytoma × CNS × Clear all
NCT03975829 2026-06-02

Pediatric Long-Term Follow-up and Rollover Study

Novartis

Phase 4 Recruiting
165 enrolled
CNSMyeloid

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT04923126 2026-02-04

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

St. Jude Children's Research Hospital

Phase 1/2 Recruiting
132 enrolled
CNS

Astrocytoma, Ganglioneuroma, Oligodendroglioma, Neoplasms, Neuroepithelial, Ganglioglioma, Neurocytoma

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