Clinical Trials Browser

Neuroinflammatory Diseases, Brain Neoplasms, Glioma, Meningioma, Multiple Sclerosis, Neoplasms, Neurilemmoma, Neurofibroma, Neuroma, Acoustic, Central Nervous System Neoplasms

NCT05581511 2025-10-14

cNF Natural Hx

Active not recruiting

500 enrolled

CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT05238909 2025-09-02

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

Enrolling by invitation

200 enrolled

CNS

Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT05891847 2025-06-10

Non-interventional Study of Patients With PN NF1 Starting Selumetinib in Russia

Active not recruiting

150 enrolled

CNS

Neurofibroma

NCT02728388 2025-05-08

Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II

Phase 2 Recruiting

30 enrolled

CNS

Neurofibroma, Neurofibromatosis 1

NCT03231306 2025-05-02

NF108-BINI

Phase 2 Completed

45 enrolled 8 charts

CNS

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT05199376 2024-02-09

CryoNF1

Phase NA Recruiting

30 enrolled

CNS

Neurofibroma, Neurofibroma, Plexiform

NCT02332902 2023-12-20

DCLNF1

Phase 2 Completed

24 enrolled 4 charts

CNS

Neurofibroma, Neurofibromatosis 1

NCT00846430 2023-08-30

Medical Treatment of "High-Risk" Neurofibromas

Phase 2 Completed

9 enrolled 9 charts

CNS

Neurofibroma, Neurofibromatosis 1

NCT03820778 2021-03-02

Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1

Phase NA Active not recruiting

10 enrolled

CNS

Neurofibromatosis, type 4, of Riccardi, Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT01347307 2020-06-18

Stereotactic Body Radiotherapy for Spine Tumors

Phase NA Completed

38 enrolled 11 charts

CNSEndocrineSarcoma

Arteriovenous Malformations, Chordoma, Meningioma, Neurilemmoma, Neurofibroma, Paraganglioma

NCT02096471 2019-01-10

MEK Inhibitor

Phase 2 Completed

19 enrolled 14 charts

CNS

Neurofibroma, Neurofibromatosis 1

NCT00021541 2018-04-17

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

Phase 2 Completed

62 enrolled 13 charts

CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT02988726 2017-07-26

Antineoplaston Therapy in Treating Patients With Neurofibroma and Schwannoma

Phase 2 Terminated

3 enrolled

CNS

Neurilemmoma, Neurofibroma, Central Nervous System Neoplasms

NCT01140360 2017-07-02

0908-09

Phase 1/2 Completed

21 enrolled 8 charts

CNS

Neurofibroma, Neurofibromatoses

NCT01275586 2017-04-12

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Phase EARLY_PHASE1 Completed

6 enrolled 7 charts

CNS

Neurofibroma, Neurofibromatoses, Neurofibroma, Plexiform

NCT01567787 2017-02-10

NF01

Phase NA Withdrawn

CNSSarcoma

Neurofibroma, Spinal Cord Neoplasms, Nerve Sheath Neoplasms, Neurofibrosarcoma

NCT00657202 2016-07-07

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

Phase EARLY_PHASE1 Completed

11 enrolled

CNS

Neurofibroma, Neurofibromatosis 1

NCT00716469 2015-04-15

PDT

Phase 1 Terminated

7 enrolled

CNS

Neurofibroma

NCT01031901 2012-02-27

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Phase 1 Completed

52 enrolled

CNS

Neurofibroma, Tuberous Sclerosis, Neurofibromatoses, Angiofibroma

NCT01218139 2010-10-11

Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients

Unknown

50 enrolled

CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Neurofibrosarcoma

Clinical Trials

Natural History Study of Patients With Neurofibromatosis Type I

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)

Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

ReNeu

Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

DoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical Margins

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

cNF Natural Hx

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

Non-interventional Study of Patients With PN NF1 Starting Selumetinib in Russia

Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II

NF108-BINI

CryoNF1

DCLNF1

Medical Treatment of "High-Risk" Neurofibromas

Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1

Stereotactic Body Radiotherapy for Spine Tumors

MEK Inhibitor

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

Antineoplaston Therapy in Treating Patients With Neurofibroma and Schwannoma

0908-09

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

NF01

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

PDT

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients