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Phase

Phase 2 23Phase 1 7Phase NA 5Phase 1/2 5Phase 3 4Phase EARLY_PHASE1 1Phase 4 1

Status

Active not recruiting 2Recruiting 1Completed 1

Sponsor Class

INDUSTRY 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Brain Neoplasms 133Glioblastoma 92Astrocytoma 44Neuroblastoma 40Glioma 40Central Nervous System Neoplasms 38Neoplasms 26Breast Neoplasms 25Neoplasm Metastasis 24Oligodendroglioma 20Gliosarcoma 19Carcinoma, Non-Small-Cell Lung 18Lymphoma, Follicular 14Recurrence 13Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Medulloblastoma 13Burkitt Lymphoma 13Testicular Neoplasms 12Lymphoma, T-Cell, Cutaneous 12Lymphoma, Non-Hodgkin 12Lymphoma, Mantle-Cell 12Lymphoma, Large-Cell, Immunoblastic 12Lymphoma, Large B-Cell, Diffuse 12Lymphoma, B-Cell, Marginal Zone 12Leukemia, Lymphocytic, Chronic, B-Cell 12Hodgkin Disease 12Sezary Syndrome 11Primary Myelofibrosis 11Mycosis Fungoides 11Leukemia, Myeloid, Chronic-Phase 11

Interventions

Control Groups 1Acceptance and Commitment Therapy 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 3 × Neurofibroma, Plexiform × CNS × Clear all
NCT07407803 2026-05-27

Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Phase 3 Recruiting
177 enrolled
CNS

Neurofibroma, Plexiform

NCT04924608 2026-03-23

KOMET

AstraZeneca

Phase 3 Active not recruiting
145 enrolled 17 charts 1 FDA
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT05913037 2025-03-06

FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas

Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

Phase 3 Active not recruiting
167 enrolled
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02471339 2022-06-14

Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain

National Institutes of Health Clinical Center (CC)

Phase 3 Completed
66 enrolled 17 charts
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

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