Announcements Trials
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Phase

Phase 2 9Phase NA 5Phase 1 4Phase EARLY_PHASE1 2Phase 1/2 1

Status

Terminated 1Recruiting 1Enrolling by invitation 1Completed 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Glioblastoma 527Brain Neoplasms 414Glioma 342Astrocytoma 239Central Nervous System Neoplasms 201Neuroblastoma 195Gliosarcoma 163Oligodendroglioma 149Medulloblastoma 118Neoplasms 113Ependymoma 72Recurrence 70Breast Neoplasms 69Sarcoma 65Melanoma 62Carcinoma, Non-Small-Cell Lung 58Osteosarcoma 57Diffuse Intrinsic Pontine Glioma 48Wilms Tumor 47Familial ependymoma 47Lymphoma 46Neoplasm Metastasis 45Optic Nerve Glioma 44Rhabdomyosarcoma 42Rhabdoid Tumor 42Lung Neoplasms 42Choroid Plexus Neoplasms 42Neuroectodermal Tumors, Primitive 38Meningeal Carcinomatosis 38Ovarian Neoplasms 37

Interventions

talimogene laherparepvec 1Talaporfin 1Sirolimus 1Deoxycholic Acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Neurofibroma × CNS × Clear all
NCT07102394 2026-05-08

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Johns Hopkins University

Phase 1 Recruiting
10 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT06300502 2026-04-22

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Massachusetts General Hospital

Phase 1 Enrolling by invitation
15 enrolled
CNS

Neurofibroma, Neurofibromatosis 1

NCT00716469 2015-04-15

PDT

Children's Hospital of Philadelphia

Phase 1 Terminated
7 enrolled
CNS

Neurofibroma

NCT01031901 2012-02-27

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

The University of Texas Health Science Center, Houston

Phase 1 Completed
52 enrolled
CNS

Neurofibroma, Tuberous Sclerosis, Neurofibromatoses, Angiofibroma

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