Announcements Trials
Browse Landscape

Phase

Phase 3 1Phase 2/3 1Phase 2 1Phase 1/2 1

Status

Terminated 3Not yet recruiting 1Active not recruiting 1

Sponsor Class

OTHER 33INDUSTRY 5NIH 3FED 2OTHER_GOV 1

Study Type

Interventional 4Observational 1

Sponsor

Cancer Type

CNS 5Dermatologic 1

Conditions

Glioblastoma 472Brain Neoplasms 306Glioma 257Neoplasms 122Astrocytoma 88Carcinoma, Non-Small-Cell Lung 76Breast Neoplasms 70Neuroblastoma 65Central Nervous System Neoplasms 61Melanoma 58Recurrence 46Lung Neoplasms 45Pancreatic Neoplasms 41Oligodendroglioma 37Ovarian Neoplasms 36Colorectal Neoplasms 36Neoplasm Metastasis 33Sarcoma 32Medulloblastoma 28Stomach Neoplasms 27Gliosarcoma 27Lymphoma 25Prostatic Neoplasms 24Head and Neck Neoplasms 24Neurofibromatosis 1 23Rhabdomyosarcoma 21Neurofibroma, Plexiform 19Esophageal Neoplasms 19Diffuse Intrinsic Pontine Glioma 19Cholangiocarcinoma 19

Interventions

emvododstat 1brolucizumab 1aflibercept 1HDAC-42 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Neurofibromatosis 2 × CNS × Clear all
NCT04759781 2026-04-23

MERLIN_001

SkylineDx

Active not recruiting
1,820 enrolled
CNSDermatologic

Melanoma, Neurofibromatosis 2

NCT07131722 2026-01-23

Study to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II

PRG Science & Technology Co., Ltd.

Phase 1/2 Not yet recruiting
25 enrolled
CNS

Neurofibromatosis 2

NCT05130866 2025-10-07

POPLAR-NF2

Recursion Pharmaceuticals Inc.

Phase 2/3 Terminated
25 enrolled
CNS

Neurofibromatosis 2

NCT03710564 2023-01-30

MERLIN

Novartis

Phase 3 Terminated
535 enrolled 14 charts
CNS

Macular Degeneration, Neurofibromatosis 2

NCT00911248 2019-04-12

PTC299 for Treatment of Neurofibromatosis Type 2

PTC Therapeutics

Phase 2 Terminated
11 enrolled
CNS

Neurofibromatosis 2, Neurofibromatoses

Data powered by HemOnc (CC BY 4.0) Colophon âš¡